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Pharm D Revised Regulations 2008 - Rajiv Gandhi University of ...

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34Second yearTheory : 3 Hrs. /Week2.1 PATHOPHYSIOLOGY (THEORY)1. Scope <strong>of</strong> the Subject: This course is designed to impart a thorough knowledge <strong>of</strong> therelevant aspects <strong>of</strong> pathology <strong>of</strong> various conditions with reference to itspharmacological applications, and understanding <strong>of</strong> basic Pathophysiologicalmechanisms. Hence it will not only help to study the syllabus <strong>of</strong> pathology, but alsoto get baseline knowledge <strong>of</strong> its application in other subject <strong>of</strong> pharmacy.2. Objectives <strong>of</strong> the Subject : Upon completion <strong>of</strong> the subject student shall be able to –a. describe the etiology and pathogenesis <strong>of</strong> the selected disease states;b. name the signs and symptoms <strong>of</strong> the diseases; andc. mention the complications <strong>of</strong> the diseases.Text books (Theory)a. Pathologic basis <strong>of</strong> disease by- Cotran, Kumar, Robbinsb. Text book <strong>of</strong> Pathology- Harsh Mohanc. Text book <strong>of</strong> Pathology- Y.M. BhindeReference books (Theory)a. Clinical <strong>Pharm</strong>acy and Therapeutics; Second edition; Roger Walker; ChurchillLivingstone publication3. Detailed syllabus and lecture wise schedule :Chapter1 Basic principles <strong>of</strong> cell injury and Adaptationa) Causes, Pathogenesis and morphology <strong>of</strong> cell injuryb) Abnormalities in lipoproteinaemia, glycogen infiltration and glycogeninfiltration and glycogen infiltration and glycogen storage diseases2 Inflammationa) Pathogenesis <strong>of</strong> acute inflammation, Chemical mediators ininflammation, Types <strong>of</strong> chronic inflammationb) Repairs <strong>of</strong> wounds in the skin, factors influencing healing <strong>of</strong> wounds3 Diseases <strong>of</strong> Immunitya) Introduction to Tand B cellsb) MHC proteins or transplantation antigensc) Immune tolerance- HypersensitivityHypersensitivity type I, II, III, IV, Biological significance, Allergydue to food, chemicals and drugs- AutoimmunityCriteria for autoimmunity, Classifications <strong>of</strong> autoimmune diseases inman, mechanism <strong>of</strong> autoimmunity, Transplantation and immunologictolerance, allograft rejections, transplantation antigens, mechanism<strong>of</strong> rejection <strong>of</strong> allograft.- Acquired immune deficiency syndrome (AIDS)

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