Pharm D Revised Regulations 2008 - Rajiv Gandhi University of ...
Pharm D Revised Regulations 2008 - Rajiv Gandhi University of ...
Pharm D Revised Regulations 2008 - Rajiv Gandhi University of ...
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744.4 BIOSTATISTICS AND RESEARCH METHODOLOGY (THEORY)Theory : 2 Hrs. /Week1. Detailed syllabus and lecture wise schedule1 Research Methodologya) Types <strong>of</strong> clinical study designs:Case studies, observational studies, interventional studies,b) Designing the methodologyc) Sample size determination and Power <strong>of</strong> a studyDetermination <strong>of</strong> sample size for simple comparative experiments,determination <strong>of</strong> sample size to obtain a confidence interval <strong>of</strong> specifiedwidth, power <strong>of</strong> a studyd) Report writing and presentation <strong>of</strong> data2 Biostatistics2.1 a) Introductionb) Types <strong>of</strong> data distributionc) Measures describing the central tendency distributions- average, median,moded) Measurement <strong>of</strong> the spread <strong>of</strong> data -range, variation <strong>of</strong> mean, standarddeviation, variance, coefficient <strong>of</strong> variation, standard error <strong>of</strong> mean.2.2 Data graphicsConstruction and labeling <strong>of</strong> graphs, histogram, piecharts, scatter plots,semilogarthimic plots2.3 Basics <strong>of</strong> testing hypothesisa) Null hypothesis, level <strong>of</strong> significance, power <strong>of</strong> test, P value, statisticalestimation <strong>of</strong> confidence intervals.b) Level <strong>of</strong> significance (Parametric data)- students t test (paired and unpaired),chi Square test, Analysis <strong>of</strong> Variance (one-way and two-way)c) Level <strong>of</strong> significance (Non-parametric data)- Sign test, Wilcoxan’s signedrank test, Wilcoxan rank sum test, Mann Whitney U test, Kruskal -Wall is test(one way ANOVA)d) Linear regression and correlation- Introduction, Pearsonn’s and Spearmann’scorrelation and correlation co-efficient.e) Introduction to statistical s<strong>of</strong>tware: SPSS, Epi Info, SAS.
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