Pharm D Revised Regulations 2008 - Rajiv Gandhi University of ...

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82Theory : 2 Hrs. /Week5.3 CLINICAL PHARMACOKINETICS ANDPHARMACOTHERAPEUTICDRUG MONITORING (THEORY)1. Introduction to Clinical pharmacokinetics.2. Design of dosage regimens:Nomograms and Tabulations in designing dosage regimen, Conversion fromintravenous to oral dosing, Determination of dose and dosing intervals, Drugdosing in the elderly and pediatrics and obese patients.3. Pharmacokinetics of Drug Interaction:a. Pharmacokinetic drug interactionsb. Inhibition and Induction of Drug metabolismc. Inhibition of Biliary Excretion.4. Therapeutic Drug monitoring:a. Introductionb. Individualization of drug dosage regimen (Variability – Genetic, Age andWeight , disease, Interacting drugs).c. Indications for TDM. Protocol for TDM.d. Pharmacokinetic/Pharmacodynamic Correlation in drug therapy.e. TDM of drugs used in the following disease conditions: cardiovasculardisease, Seizure disorders, Psychiatric conditions, and Organ transplantations.5. Dosage adjustment in Renal and hepatic Disease.a. Renal impairmentb. Pharmacokinetic considerationsc. General approach for dosage adjustment in Renal disease.d. Measurement of Glomerular Filtration rate and creatinine clearance.e. Dosage adjustment for uremic patients.f. Extracorporeal removal of drugs.g. Effect of Hepatic disease on pharmacokinetics.6. Population Pharmacokinetics.a. Introduction to Bayesian Theory.b. Adaptive method or Dosing with feed back.c. Analysis of Population pharmacokinetic Data.7. Pharmacogeneticsa. Genetic polymorphism in Drug metabolism: Cytochrome P -450 Isoenzymes.b. Genetic Polymorphism in Drug Transport and Drug Targets.c. Pharmacogenetics and Pharmacokinetics/Pharmacodynamic considerations
83APPENDIX-BCONDITIONS TO BE FULFILLED BY THEACADEMIC TRAINING INSTITUTION1) Any authority or institution in India applying to the Pharmacy Council of India forapproval of courses of study for Pharm.D. and Pharm.D. (Post Baccalaureate) under subsection(1) of section 12 of the Pharmacy Act, 1948 shall comply with the infrastructuralfacilities as prescribed by the Pharmacy Council of India from time to time.2) Pharm.D. and Pharm.D. (Post Baccalaureate) programmes shall be conducted only inthose institutions which -a) are approved by the Pharmacy Council of India for Pharm. D course as providedunder section 12 of the Pharmacy Act, 1948;b) have 300 bedded hospital attached to it.(i) Hospital Details1. Institution with their own hospital of minimum 300 beds.2. Teaching hospital recognised by the Medical Council of India or University,or a Government hospital not below the level of district headquarter hospitalwith 300 beds with clearly defined Memorandum of Understanding includinghousing pharmacy practice department with minimum carpet area of 30 squarefeet per student along with consent to provide the professional manpower tosupport the programme.3. Corporate type hospital with minimum 300 beds with clearly definedMemorandum of Understanding including housing pharmacy practicedepartment with minimum carpet area of 30 square feet per student along withconsent to provide the professional manpower to support the programme.4. Number of institutions which can be attached to one hospital shall be restrictedby the student pharmacist to bed ratio of 1:10.(ii) Specialtya) Tertiary care hospitals are desirableb) Medicine[compulsory], and any three specialization of the following1. Surgery2. Pediatrics3. Gynecology and obstetrics4. Psychiatry5. Skin and VD6. Orthopedics(iii) Location of the Hospital
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Sixth Year:5Internship or residency
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12. Declaration of Class9Class shal
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11(v) Final evaluation of project w
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151.1 HUMAN ANATOMY & PHYSIOLOGY (P
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Theory : 2 Hrs. /Week171.2 PHARMACE
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195. Linimentsa. Liniment of turpen
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214 Lipid metabolism: Oxidation of
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231.4 PHARMACEUTICAL ORGANIC CHEMIS
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2512 Mechanism of aldol condensatio
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271.5 PHARMACEUTICAL INORGANIC CHEM
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291.5 PHARMACEUTICAL INORGANIC CHEM
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