;1849.] Cases of Pneumonia Typhoides. 4istill continued, the patient must sink. Bronchial breathing hadtaken the place of the crepitus, <strong>and</strong> the prostration was great.Acetate of lead was now given, combined with suitable dosesof calomel <strong>and</strong> opium. In less than thirty-six hours, the perspiration<strong>and</strong> expectoration were reduced to an ordinary quantitythe pulse was below a hundred, <strong>and</strong> the delirium gone. Crepitantrale in right side returned. The gums had the blue border,<strong>and</strong> gave slight evidence of the action of calomel ; convalescencewas almost or quite established.Case II. Mrs. H., aged 45, of feeble constitution, had beenfrequently sick, <strong>and</strong> w^as at the time of the attack worn downby nursing. She was taken with a chill, followed by severeheadache <strong>and</strong> neuralgia, pains of the back <strong>and</strong> limbs, <strong>and</strong> aviolent lancinating pain in the left side near the border of theribs extending thence to the shoulder of the same side. Shehad a dry cough with trifling frothy expectoration, pulse 120<strong>and</strong> feeble, tongue slightly coated white, <strong>and</strong> moist, skin hot <strong>and</strong>dry. Percussion clear <strong>and</strong> a perfectly natural, vesicular murmur.Two days after plueritis extended to the lungs proper;the pain abated <strong>and</strong> a brick-dust colored expectoration appeared.Uterine hemorrhage also set in, not profuse, but sufficientto increase rapidly the debility. To check this hemorrhage,rather than with a view to operate on the pulmonic inflammation,'I gave acetate of lead, two grain doses, every four hours,united with calomel <strong>and</strong> opium, which she was taking. Thenext day the hemorrhage was less, but not entirely arrested,<strong>and</strong> all the other symptoms decidedly better ; <strong>and</strong> what maybe particularly mentioned, the skin was moist. The followingday, slight effects of calomel <strong>and</strong> lead on the gums were evident; continuing the same medicine in diminished doses, convalesencewas established, accompanied with a very soremouth.Observing the sudden effect of the lead here, <strong>and</strong> reflectingupon it, in connection with the case of Mr. G. S., I resolved togive it a trial in the next case which mio;ht occur, even shouldthere be no excessive evacuation which it might be desirableto arrest ; solely with a view to its alterative effect upon thecapillary structure.Case III. Mr. P. W., a young man of good constitution,sent for me at 6 A. M., the 12th Febuary last. He was takenthe night before with a chill which lasted an hour, which wasfollowed by heat <strong>and</strong> pain in tiie right side, near the border ofthe false ribs. He had complained of severe pain in the headalso, but -was now delirious. His pulse was 120 <strong>and</strong> feeble.
46 Cases of Pneumonia Typhoides. [January,tongue coated with a thick yellowish coat, <strong>and</strong> moist, skin hot<strong>and</strong> diy; he had vomited a number of times <strong>and</strong> had frequentdischarges from the bowels ; coughed frequently without expectorating.His breathing was oppressed, his countenancecontracted, eyes icterode <strong>and</strong> dull. Rale crepitans over theright latteral region of the chest.'^i Tar. Emetic, or. ss. ) •r\ r u•o 1 u TV/rn IOnce m lour hours.Sulph. Magnesia, 3 ss. )The next day's report was, that he had not vomitted since hetook the medicine, <strong>and</strong> his bowels had moved twice only. Deliriumcontinued, pulse 110, <strong>and</strong> skin moist, slight dulness onpercussion, <strong>and</strong> tubular breathing had taken tne place of thecrepitus. Same medicine continued.14th. All was worse, constant delirum ; the eye's had the peculiartyphoid stare; coughed little, expectorated nothing;pulse small <strong>and</strong> 130, skin dry.^ CalomeL m\ ss. 1 t? c -u'•Ti I T J r-k « [ tiVery lour bourse1 ulv. Ipecac, <strong>and</strong> Upii, aa gr. ss. )16th, No amendment.I^. Calomel, gr. j. ^Opii, gr. i. > Every two hours.Camphor, gr. ij.)16th, 10 A. M. Still worse, no cough', rapid bronchial breaithingof the "blowing kind," quite up to the scapula <strong>and</strong> clavicle.I now added to the last prescription two grains of lead, evefytwo hours.17th, 9 A. M. When I entered the foom this morning,- helooked up, <strong>and</strong> vv^ith a natural expi'ession of countenance, <strong>and</strong>in a perfectly rational manner, jocosely asked me whether I wastrying in how short a time I could treat a man to death. Andhe was sweating profusely, with pulse down to 100, <strong>and</strong> breathingcomparatively easy. Cough had returned also, with a fre'eexj)ectoration.On the 18th the gums were slightly affected, <strong>and</strong> a rapid eoAvalesencefollowed.We are aware that the recovery of three patients from attacksof severe inflammation during the use of acetate of lead, statedas a simple, isolated fact, can be of but little value. But if thesecases, in their symptoms, all point to a certain pathological condition,state, or stage of disease, in which the ordinary remediesseemed to lack power to effect a favorable change, <strong>and</strong> whichchange seemed to be produced by lead ; <strong>and</strong> if to this fact we*can add a rational explanation, founded upon an analogous operationof lead in other diseases, we certainly go as far as thref^"
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