Impact on Patient Care
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CA-MRSA and Clindamycin:Is there inducible resistance?S. aureus soft tissue infecti<strong>on</strong>• Penicillin• Erythromycin• Clindamycin• Levofloxacin• Oxacillin• VancomycinRRSRRSIs this phenotypeauthorizati<strong>on</strong> to prescribeclindamycin?(+) D-test ~ (+erm)(Good chance clindamycin will fail)Frank AL, et al. Pediatr Infect Dis J 2002;21:530-4. Lewis JS, et al. Clin Infect Dis. 2005 Jan 15;40(2):280-5Levin TP, et al. Antimicrob Agents Chemother 2005;49:1222-4. 26