Impact on Patient Care
Download (PDF, 10.84 MB) - Health Care Improvement Foundation
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The Rules of Antibiotic Resistance1. Given enough antibiotic and time, resistance will appear2. Resistance is progressive, moving from low tointermediate to high levels3. Organisms that are resistant to <strong>on</strong>e antibiotic will likelybecome resistant to others ( “cross-resistance”)4. Once selected, drug resistance will not disappear,although it may decline5. Select antibiotics to treat “both” patients!Levy SB NEJM 1998; 338:1376-8.8