How to handle liver biopsy specimens
Prof B Portmann 11.20 - Virtual Pathology at the University of Leeds
Prof B Portmann 11.20 - Virtual Pathology at the University of Leeds
- No tags were found...
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
Copper and copper associated protein<br />
• Copper easily removed by formal saline<br />
(especially if acidic)<br />
•Copper-binding protein unaffected by fixation<br />
• Early Wilson :<br />
- Cy<strong>to</strong>solic Cu highly soluble + <strong>to</strong>o small<br />
<strong>to</strong> be seen his<strong>to</strong>logically<br />
- Lysosomal Cu binding protein may not<br />
be significant yet<br />
⇒ negative staining does not exclude WD
Change language