BIOT

Westin San Diego
Opal
Emerging Technologies
Protein & Molecular Engineering
J. Latone, G. M. Thurber, I. R. Wheeldon, Organizers
R. Bott, M. Kim, Organizers, Presiding
2:00 487. Artificial TCA cycle metabolon: Direct evidence for metabolon formation and substrate
channeling. K. Garcia, B. Bulutoglu, F. Wu, S.D. Minteer, S. Banta
2:20 488. Osteogenic differentiation of stem cells promoted by the assemblies of genetically engineered
bacteriophage. C. Mao
2:40 489. Bacterial inner membrane display for screening a naïve antibody library to isolate antibodies that
bind survivin. P. Moghaddam-Taaheri, A.J. Karlsson
3:00 490. Rational design and development of polysialic acid-binding peptides: Implications in neural stem
cell purification. D. Shastry, P. Karande
3:20 Intermission.
3:40 491. Constructing new bioluminescent tools with minimally perturbed luciferins. C.M. Rathbun, R.C.
Steinhardt, W.B. Porterfield, K. Jones, D. McCutcheon, M.A. Paley, J.A. Prescher
4:00 492. Circle Akt In: Macrocycles against phosphorylated Akt. A. Nag, S. Das, J.R. Heath
4:20 493. Switchable protein sensors and enzyme reactions based on dynamic DNA assembly. R.P. Chen, D.
Blackstock, Q. Sun, W. Chen
4:40 494. RNA length affects form and function of the Type I CRISPR-Cas surveillance complex. M. Luo,
C. Beisel
Westin San Diego
Crystal I
Quality by Design for Biopharmaceuticals
QbD Case Studies: Process Validation
Section E
S. Singh, C. Torigoe, Organizers
K. A. Barnthouse, M. T. Schmidt, Organizers, Presiding
2:00 495. Manufacturability assessment tool for effective decision-making and efficient process
development: Development and applications. K. Brower, R.A. Patil, D.A. Shah, J. Walther, N.M. Troccoli,
T.A. Vetter, V. Warikoo