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ADVERTORIAL<br />

Do you have an<br />

BY KENNETH N. WOLINER, M.D., A.B.F.M.<br />

Optimal Thyroid?<br />

“I have tried every diet known to man (or moms) these last few<br />

years –<br />

to no avail.”<br />

Alyson continued to tell me her story. “For example, this past<br />

summer, my best friend flew me to their home in Sonoma for an<br />

entire month. We ate nothing but organic everything, lean protein,<br />

I drank 150 ounce-plus of water a day and did a high intensity<br />

workout every morning mixing up interval training with boot camp<br />

at her gym. In exactly 30 days – I lost a grand total of THREE pounds.<br />

I didn’t even lose the initial ‘water weight’ everyone else loses.”<br />

I empathized, “It’s hard to stay motivated with minimal results.”<br />

“I’m willing to starve myself, if that would work. I even did two<br />

rounds of hCG. My wallet’s lighter, but that’s about it.”<br />

“The FDA recently published a website, www.fda.gov/hcgdiet,<br />

detailing how hCG diet products are illegal, and how restrictive diets<br />

such as that one can cause electrolyte disturbances, an irregular<br />

heartbeat and are potentially fatal.” I continued, “But looking at your<br />

diet history, I don’t think the problem is one of eating too much.”<br />

“Dr. Woliner, what else could it be? I have a friend that blew up<br />

taking Abilify for her depression, and another while on Actos for<br />

diabetes, but I’m not on any medications.”<br />

“It’s true that many drugs have weight gain as a common side<br />

effect [1]. But there are other causes of weight gain. With your<br />

other symptoms of cold intolerance, fatigue, and constipation, I’m<br />

thinking that you have an untreated thyroid condition [2].”<br />

“I begged my other doctors to treat me for that, but they all said<br />

no.”<br />

“Some doctors focus too much on lab tests without considering<br />

the patient’s history and physical exam findings [3]. Thyroid<br />

hormone resistance is more common than people realize.”<br />

Alyson sat with a puzzled look on her face. “So, even if these<br />

doctors said my tests were normal, I might still have a thyroid<br />

problem? [4]”<br />

“The word ‘normal’ has many meanings. There is a difference<br />

between ‘common’ and ‘optimal’ [5]. Rather than using a range that<br />

includes people who are overweight and being treated for high<br />

cholesterol and other conditions, perhaps it would be better to use<br />

narrower ranges of persons who feel ‘dandy’ [6].”<br />

“Does anyone even use that word anymore?”<br />

“My practice is built on patient-to-patient referrals. Just liking my<br />

bedside manner is not enough to convince your friends to see me.<br />

You have to glow. So yes, I do plan on making you feel dandy.”<br />

After finishing Alyson’s physical exam, my staff used our Korr<br />

indirect calorimetry machine to measure her metabolic rate [7].<br />

“You’re at ‘minus 20%’. That’s one of slowest metabolism’s I’ve ever<br />

seen!”<br />

“How do we fix that?”<br />

“I use a holistic approach that combines behavior changes, diet,<br />

exercise, supplements, and of course medications [8,9]. I prefer to<br />

use T3 based drugs as they have been shown to cause significantly<br />

more weight loss than T4 drugs such as Synthroid alone [10].”<br />

As I ramped up Alyson’s dose of thyroid medication, her fatigue<br />

and other symptoms began to resolve. To be on the safe side, I<br />

periodically rechecked her EKG and bone density, which remained<br />

normal [11].<br />

“Dr. Woliner, your scale says I only lost 49 pounds, but at home,<br />

naked, I’m down 51!”<br />

“<br />

Thyroid hormone resistance<br />

is more common than<br />

people realize.<br />

“<br />

REFERENCES:<br />

[1] Singh T. Aripiprazole-induced weight gain. Psychiatry (Edgmont).<br />

2005 Jun;2(6):19. [2] de Moura Souza A, Sichieri R.<br />

Association between serum TSH concentration within the normal<br />

range and adiposity. Eur J Endocrinol. 2011 Jul;165(1):11-5.<br />

[3] Kalra S, Khandelwal SK. Why are our hypothyroid patients<br />

unhappy? Is tissue hypothyroidism the answer? Indian J<br />

Endocrinol Metab. 2011 Jul;15(Suppl 2):S95-8.<br />

[4] Dickey RA, Wartofsky L, Feld S. Optimal thyrotropin level: normal<br />

ranges and reference intervals are not equivalent. Thyroid. 2005<br />

Sep;15(9):1035-9.<br />

[5] Gurnell M, Halsall DJ, Chatterjee VK. What should be done when<br />

thyroid function tests do not make sense? Clin Endocrinol (Oxf).<br />

2011 Jun;74(6):673-8.<br />

[6] Shomon M. The Optimal Treatment for Hypothyroidism –<br />

Interview with Dr. Ken Woliner. http://thyroid.about.com. January<br />

10, 2011.<br />

[7] Kim B. Thyroid hormone as a determinant of energy expenditure<br />

and the basal metabolic rate. Thyroid. 2008 Feb;18(2):141-4.<br />

[8] Singh P, et al. The impact of yoga upon female patients suffering<br />

from hypothyroidism. Complement Ther Clin Pract. 2011<br />

Aug;17(3):132-4.<br />

[9] Schomburg L. Treating Hashimoto’s thyroiditis with selenium: no<br />

risks, just benefits? Thyroid. 2011 May;21(5):563-4.<br />

[10] Celi FS, et al. Metabolic effects of liothyronine therapy in<br />

hypothyroidism: a randomized, double-blind, crossover trial of<br />

liothyronine versus levothyroxine. J Clin Endocrinol Metab. 2011<br />

Nov; 96(11): 3466-74.<br />

[11] Ricken R, et al. Long-term treatment with supraphysiological<br />

doses of thyroid hormone in affective disorders - effects<br />

on bone mineral density. J Affect Disord. 2012<br />

Jan;136(1-2):e89-94.<br />

Dr. Kenneth Woliner is a board-certified family medicine<br />

physician in private practice in Boca Raton. He can be reached<br />

at: Holistic Family Medicine; 9325 Glades Road, #104,<br />

Boca Raton, FL 3343 ~ 561-314-0950<br />

the PARKLANDER knw6@cornell.edu ; www.holisticfamilymed.com<br />

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