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Helicobacter pylori - Portal Neonatal

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16<br />

Congenital problems of the gastrointestinal tract<br />

In cases in which the diagnosis is not clear on<br />

abdominal X-ray or in which midgut malrotation<br />

or volvulus is suspected, a limited upper gastrointestinal<br />

contrast study is indicated. The classical<br />

finding in cases of malrotation is that the duodenojejunal<br />

flexure lies to the right side of the<br />

spine instead of in its normal left-sided position<br />

(Figure 2.3). This finding should prompt urgent<br />

surgical treatment, because of the risk of co-existing<br />

midgut volvulus. The contrast study may also<br />

identify the presence of a stenotic segment or<br />

complete obstruction.<br />

Cases of lower ileal stenosis or atresia are often<br />

more difficult to diagnose and a contrast enema is<br />

invaluable in distinguishing between ileal and<br />

colonic obstruction and could be therapeutic in<br />

cases of meconium ileus (see below).<br />

Conditions affecting the duodenum<br />

Duodenal atresia, duodenal stenosis and annular<br />

pancreas are the most common congenital condi-<br />

Figure 2.2 Abdominal X-ray of an infant with duodenal<br />

atresia showing the ‘double bubble’ appearance<br />

characteristic of duodenal obstruction.<br />

tions to affect the duodenum. All are capable of<br />

giving rise to duodenal obstruction. The incidence<br />

is reported to be between 1 in 5000 and 1 in 10 000<br />

live births. 8<br />

Explanations of the etiology of duodenal atresias<br />

are not universally accepted. Unlike atresias of the<br />

ileum, they are not thought to be due to vascular<br />

accidents and the most widely accepted explanation<br />

is that of failure of recanalization of the<br />

intestinal lumen during early embryonic development.<br />

Classification<br />

There are four basic types of duodenal obstruction<br />

(Figure 2.4). In type 1 there is a stenosis of the<br />

duodenum resulting from a diaphragm or web<br />

partially or totally occluding the lumen. Owing to<br />

the incomplete nature of the obstruction, cases<br />

Figure 2.3 Upper gastrointestinal contrast study of a<br />

case of malrotation. The contrast is seen within the<br />

duodenum (D) and flowing into the upper jejunum (J),<br />

both of which lie completely to the right of the midline.

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