DESCRIPTIONS OF MEDICAL FUNGI

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18 Descriptions of Medical Fungi Aspergillus fumigatus Fresenius a b 10 μm b 10 μm b 10 μm Aspergillus fumigatus (a) culture and (b) conidial head morphology. Note: Uniseriate row of phialides on the upper two thirds of the vesicle. Antifungal Susceptibility: A. fumigatus complex (Australian National data); MIC µg/mL. No 16 AmB 523 2 40 122 167 130 58 3 1 VORI 486 1 1 27 112 259 54 11 13 5 3 POSA 415 7 27 50 69 162 79 13 7 0 0 1 ITRA 523 1 6 17 41 74 244 115 15 5 1 4 ANID 249 5 170 52 18 1 1 2 MICA 249 91 95 48 12 2 1 CAS 264 2 22 91 106 24 12 1 1 5
Descriptions of Medical Fungi 19 Aspergillus lentulus Balajee & Marr Aspergillus lentulus appears to be widely distributed in soil and is now well documented as a causative agent of invasive aspergillosis in immunosuppressed patients. It is part of the A. fumigatus complex. RG-2 organism. Morphological Description: Colonies of A. lentulus are suede-like to floccose, white with interspersed grey-green patches of conidia (conidiation is slow to poor in most strains). Conidial heads are short, columnar and uniseriate. Conidiophore stipes are smooth-walled, sometimes sinuous and are often constricted at the neck. Vesicles are usually subglobose in shape. Conidia globose to broadly ellipsoidal (2-3.2 µm in diameter), smooth to finely roughened. Molecular Identification: A. lentulus can be distinguished from other members of the section Fumigati by sequence analysis of β-tubulin, calmodulin and actin genes (Samson et al. 2007, Balajee et al. 2005b). ITS sequencing is not recommended. a b 10 μm b 10 μm Aspergillus lentulus (a) culture and (b) conidial head morphology.
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DESCRIPTIONS OF MEDICAL FUNGI

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