DESCRIPTIONS OF MEDICAL FUNGI

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24 Descriptions of Medical Fungi Aspergillus niger van Tieghem a b 10 μm Aspergillus niger (a) Culture and (b) conidial head morphology. Note: Conidial heads are biseriate, large, globose, dark brown, becoming radiate with the phialides borne on metulae.
Descriptions of Medical Fungi 25 Aspergillus terreus complex Aspergillus section Terrei (Gams et al. 1985); Aspergillus terreus complex includes species with biseriate, columnar conidial heads in shades of buff to brown (Raper and Fennell 1965). The most important species of this section is A. terreus, which is ubiquitous in the environment (Samson et al. 2011). Two other species have been reported as medical pathogens, A. alabamensis and A. niveus. Molecular Identification: A. terreus can be distinguished from other members of the section Terrei by sequence analysis of β-tubulin, calmodulin and actin genes. ITS sequencing is sufficient to identify to species complex level only. Aspergillus terreus Thom Aspergillus terreus occurs commonly in soil and is occasionally reported as a pathogen of humans and animals. RG-2 organism. Morphological Identification: On Czapek Dox agar, colonies are typically suedelike and cinnamon-buff to sand-brown in colour with a yellow to deep dirty brown reverse. Conidial heads are compact, columnar (up to 500 x 30-50 µm in diameter) and biseriate. Metulae are as long as the phialides. Conidiophore stipes are hyaline and smooth-walled. Conidia are globose to ellipsoidal (1.5-2.5 µm in diameter), hyaline to slightly yellow and smooth-walled. Key Features: Cinnamon-brown cultures, conidial heads biseriate with metulae as long as the phialides. References: Raper and Fennell (1965), Domsch et al. (1980), McGinnis (1980), Onions et al. (1981), Samson and Pitt (1990), Samson et al. (1995), de Hoog et al. (2000) and Klich (2002). Antifungal Susceptibility: A. terreus (Australian National data); MIC µg/mL. No 16 AmB 72 1 3 11 29 24 3 1 VORI 69 4 13 32 16 1 2 1 POSA 59 1 10 8 23 13 2 2 ITRA 72 4 3 9 17 35 4
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DESCRIPTIONS OF MEDICAL FUNGI

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