VA/DoD CLINICAL PRACTICE GUIDELINE FOR OPIOID THERAPY FOR CHRONIC PAIN

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DRAFT 3 - DO NOT DISTRIBUTE VA/DoD Clinical Practice Guideline for Opioid Therapy for Chronic Pain 55. Helmer DA, Chandler HK, Quigley KS, Blatt M, Teichman R, Lange G. Chronic widespread pain, mental health, and physical role function in OEF/OIF veterans. Pain Med. Oct 2009;10(7):1174- 1182. 56. Vanderlip ER, Sullivan MD, Edlund MJ, et al. National study of discontinuation of long-term opioid therapy among veterans. Pain. Dec 2014;155(12):2673-2679. 57. Martin BC, Fan MY, Edlund MJ, Devries A, Braden JB, Sullivan MD. Long-term chronic opioid therapy discontinuation rates from the TROUP study. J Gen Intern Med. Dec 2011;26(12):1450- 1457. 58. Zedler B, Xie L, Wang L, et al. Risk factors for serious prescription opioid-related toxicity or overdose among Veterans Health Administration patients. Pain Med. Nov 2014;15(11):1911-1929. 59. Bohnert AS, Valenstein M, Bair MJ, et al. Association between opioid prescribing patterns and opioid overdose-related deaths. JAMA. Apr 6 2011;305(13):1315-1321. 60. Harden RN. Chronic opioid therapy: Another reppraisal. APS Bulletin. 2002;12(1). 61. Im JJ, Shachter RD, Oliva EM, Henderson PT, Paik MC, Trafton JA. Association of care practices with suicide attempts in US veterans prescribed opioid medications for chronic pain management. J Gen Intern Med. Jul 2015;30(7):979-991. 62. Campbell G, Bruno R, Darke S, Degenhardt L. Associations of borderline personality with pain, problems with medications and suicidality in a community sample of chronic non-cancer pain patients prescribed opioids for pain. Gen Hosp Psychiatry. Sep-Oct 2015;37(5):434-440. 63. Merrill JO, Von Korff M, Banta-Green CJ, et al. Prescribed opioid difficulties, depression and opioid dose among chronic opioid therapy patients. Gen Hosp Psychiatry. Nov-Dec 2012;34(6):581-587. 64. Davidson CL, Babson KA, Bonn-Miller MO, Souter T, Vannoy S. The impact of exercise on suicide risk: Examining pathways through depression, PTSD, and sleep in an inpatient sample of veterans. Suicide Life Threat Behav. Jun 2013;43(3):279-289. 65. Seal KH, Shi Y, Cohen G, et al. Association of mental health disorders with prescription opioids and high-risk opioid use in US veterans of Iraq and Afghanistan. JAMA. Mar 7 2012;307(9):940-947. 66. Turner BJ, Liang Y. Drug overdose in a retrospective cohort with non-cancer pain treated with opioids, antidepressants, and/or sedative-hypnotics: Interactions with mental health disorders. J Gen Intern Med. Aug 2015;30(8):1081-1096. 67. Peirce GL, Smith MJ, Abate MA, Halverson J. Doctor and pharmacy shopping for controlled substances. Med Care. Jun 2012;50(6):494-500. 68. Andrews J, Guyatt G, Oxman AD, et al. Grade guidelines: 14. Going from evidence to recommendations: The significance and presentation of recommendations. J Clin Epidemiol. Jul 2013;66(7):719-725. 69. Guyatt GH, Oxman AD, Kunz R, et al. Going from evidence to recommendations. BMJ. May 10 2008;336(7652):1049-1051. 70. Newberry SJ, Ahmadzai N, Motala A, et al. AHRQ methods for effective health care. Surveillance and identification of signals for updating systematic reviews: Implementation and early experience. Rockville (MD): Agency for Healthcare Research and Quality (US); 2013. 71. Guirguis-Blake J, Calonge N, Miller T, Siu A, Teutsch S, Whitlock E. Current processes of the U.S. Preventive Services Task Force: Refining evidence-based recommendation development. Ann Intern Med. Jul 17 2007;147(2):117-122. 72. The guidelines manual. London: National Institute for Health and Care Excellence;2012. http://www.nice.org.uk/article/pmg6/resources/non-guidance-the-guidelines-manual-pdf. 73. Martinez Garcia L, McFarlane E, Barnes S, Sanabria AJ, Alonso-Coello P, Alderson P. Updated recommendations: An assessment of NICE clinical guidelines. Implement Sci. 2014;9:72. 74. White CM, Ip S, McPheeters M, et al. AHRQ methods for effective health care using existing systematic reviews to replace de novo processes in conducting comparative effectiveness reviews. February 2017 Page 182 of 192
DRAFT 3 - DO NOT DISTRIBUTE VA/DoD Clinical Practice Guideline for Opioid Therapy for Chronic Pain Methods guide for effectiveness and comparative effectiveness reviews. Rockville (MD): Agency for Healthcare Research and Quality (US); 2008. 75. Institute of Medicine (US) Committe on Standards for Developing Trustworthy Clinical Practice Guidelines, R Graham, M Mancher, D Miller Wolman, et al., editors. Clinical practice guidelines we can trust. Washington, DC: National Academies Press;2011. 76. Schunemann HJ, Fretheim A, Oxman AD. Improving the use of research evidence in guideline development: 10. Integrating values and consumer involvement. Health Res Policy Syst. 2006;4:22. 77. Bertakis KD, Azari R. Patient-centered care is associated with decreased health care utilization. J Am Board Fam Med. May-Jun 2011;24(3):229-239. 78. Robinson JH, Callister LC, Berry JA, Dearing KA. Patient-centered care and adherence: Definitions and applications to improve outcomes. J Am Acad Nurse Pract. Dec 2008;20(12):600-607. 79. Doran GT. There's a S.M.A.R.T. way to write management's goals and objectives. Management Review. 1981;70(11):35-36. 80. O'Keeffe M, Purtill H, Kennedy N, et al. Comparative effectiveness of conservative interventions for nonspecific chronic spinal pain: Physical, behavioral/psychologically informed, or combined? A systematic review and meta-analysis. J Pain. Feb 1 2016. 81. Kamper SJ, Apeldoorn AT, Chiarotto A, et al. Multidisciplinary biopsychosocial rehabilitation for chronic low back pain: Cochrane systematic review and meta-analysis. BMJ. 2015;350:h444. 82. Buhrman M, Gordh T, Andersson G. Internet interventions for chronic pain including headache: A systematic review. Internet Interventions.4:17-34. 83. Chou R, Deyo R, Friedly J, et al. AHRQ comparative effectiveness reviews. Noninvasive treatments for low back pain. Rockville (MD): Agency for Healthcare Research and Quality (US); 2016. 84. Varatharajan S, Ferguson B, Chrobak K, et al. Are non-invasive interventions effective for the management of headaches associated with neck pain? An update of the Bone and Joint Decade Task Force on Neck Pain and Its Associated Disorders by the Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration. Eur Spine J. Jul 2016;25(7):1971-1999. 85. Cramer H, Lauche R, Haller H, Dobos G. A systematic review and meta-analysis of yoga for low back pain. Clin J Pain. May 2013;29(5):450-460. 86. Edlund MJ, Martin BC, Russo JE, DeVries A, Braden JB, Sullivan MD. The role of opioid prescription in incident opioid abuse and dependence among individuals with chronic noncancer pain: The role of opioid prescription. Clin J Pain. Jul 2014;30(7):557-564. 87. Huffman KL, Shella ER, Sweis G, Griffith SD, Scheman J, Covington EC. Nonopioid substance use disorders and opioid dose predict therapeutic opioid addiction. J Pain. Feb 2015;16(2):126-134. 88. Boscarino JA, Rukstalis M, Hoffman SN, et al. Risk factors for drug dependence among out-patients on opioid therapy in a large US health-care system. Addiction. Oct 2010;105(10):1776-1782. 89. Boscarino JA, Rukstalis MR, Hoffman SN, et al. Prevalence of prescription opioid-use disorder among chronic pain patients: Comparison of the DSM-5 vs. DSM-4 diagnostic criteria. J Addict Dis. Jul-Sep 2011;30(3):185-194. 90. Park TW, Saitz R, Ganoczy D, Ilgen MA, Bohnert AS. Benzodiazepine prescribing patterns and deaths from drug overdose among US veterans receiving opioid analgesics: Case-cohort study. BMJ. 2015;350:h2698. 91. Reisfield GM, Webster LR. Benzodiazepines in long-term opioid therapy. Pain Med. Oct 2013;14(10):1441-1446. 92. Banta-Green CJ, Merrill JO, Doyle SR, Boudreau DM, Calsyn DA. Opioid use behaviors, mental health and pain--development of a typology of chronic pain patients. Drug Alcohol Depend. Sep 1 2009;104(1-2):34-42. 93. Stojadinovic A, Auton A, Peoples GE, et al. Responding to challenges in modern combat casualty care: Innovative use of advanced regional anesthesia. Pain Med. Jul-Aug 2006;7(4):330-338. February 2017 Page 183 of 192
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Appendix D: Drug Tables A. Short-ac
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Short-Acting Opioid Initial Oral Do
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Short-Acting Opioid Initial Oral Do
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Short-Acting Opioid Tramadol (alone
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Long-Acting/ER Opioids 1 Buprenorph
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Long-Acting/ER Opioids 1 Hydrocodon
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Long-Acting/ER Opioids 1 Initial Do
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3 CYP-3A4 inhibiting agents include
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VA/DoD CLINICAL PRACTICE GUIDELINE FOR OPIOID THERAPY FOR CHRONIC PAIN

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