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Daily Heritage July 24

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Quake Edition 114.qxp_Layout 1 7/21/17 9:05 PM Page 6<br />

Tips on<br />

dementia<br />

DEMENTIA IS a broad category<br />

of brain diseases that cause<br />

a long term and often gradual<br />

decrease in the ability to think<br />

and remember that is great<br />

enough to affect a person's daily<br />

functioning. Other common<br />

symptoms include emotional<br />

problems, problems with language,<br />

and a decrease in motivation<br />

• Dementia is mainly a disease<br />

of old age.<br />

• About 47m people around<br />

the world are living with dementia.<br />

• It is expected to rise to<br />

115m by 2050.<br />

• One in three dementia cases<br />

can be prevented<br />

• People with dementia may<br />

have problems with short-term<br />

memory, keeping track of a<br />

purse or wallet, paying bills, planning<br />

and preparing meals, remembering<br />

appointments or<br />

traveling out of the neighborhood.<br />

WWW.DAILYHERITAGE.COM.GH<br />

DAILY HERITAGE MONDAY, JULY <strong>24</strong>, 2017<br />

&Env.<br />

Cow antibodies for AIDS cure soon<br />

IN A significant find, a team<br />

of researchers has reported<br />

for the first time elicitation<br />

of powerful, HIV-blocking<br />

antibodies in cows in a matter<br />

of weeks -- a process<br />

that usually takes years in humans<br />

-- paving the way for developing a<br />

broadly effective AIDS vaccine in<br />

the near future.<br />

According to the study, published<br />

in the prestigious journal<br />

Nature, the unexpected discovery<br />

in cows is providing clues for important<br />

questions at a moment<br />

when new energy has infused HIV<br />

vaccine research.<br />

"One approach to a preventive<br />

HIV vaccine involves trying to<br />

elicit broadly neutralising antibodies<br />

in healthy people, but so far<br />

the experiments have been unsuccessful,<br />

in both human and animal<br />

studies," said lead author Devin<br />

Sok, Director, Antibody Discovery<br />

and Development at the International<br />

AIDS Vaccine Initiative<br />

(IAVI).<br />

"This experiment demonstrates<br />

that not only is it possible to produce<br />

these antibodies in animals,<br />

but we can do so reliably, quickly,<br />

and using a relatively simple immunisation<br />

strategy when given in<br />

the right setting," Sok added.<br />

Scientists have known that<br />

some people living with chronic<br />

HIV infection produce broadly<br />

neutralising antibodies (bnAbs),<br />

which can overcome the high levels<br />

of diversity of HIV.<br />

One type of bnAb uses long,<br />

arm-like loops that are capable of<br />

reaching concealed areas on the<br />

virus's surface to block infection.<br />

The scientists had a question:<br />

what would happen if they immunise<br />

cows with an HIV immunogen?<br />

"The answer began with a single<br />

protein on HIV's surface that<br />

serves as a bnAb target -- develop<br />

an antibody that recognises variants<br />

of this protein on different<br />

HIV viruses and<br />

you'll likely be protected<br />

from all of them," the<br />

study said.<br />

One of the many tricks<br />

that HIV uses to prevent<br />

humans from developing<br />

the right antibodies is to<br />

display irrelevant forms of<br />

this protein to distract the<br />

immune system.<br />

Scientists thought they<br />

had overcome this challenge<br />

by developing an immunogen<br />

called "BG505<br />

SOSIP", which closely<br />

mimics the protein target.<br />

In the new study, four<br />

cows immunised with<br />

"BG505 SOSIP" elicited<br />

"bnAbs" to HIV within 35-<br />

52 days.<br />

In comparison, it takes HIVpositive<br />

humans multiple years to<br />

develop comparable responses,<br />

and only 5-15% even develops<br />

them at all.<br />

"Cows cannot be infected with<br />

HIV, of course. But these findings<br />

illuminate a new goal for HIV vaccine<br />

researchers: by increasing the<br />

number of human antibodies with<br />

long loops, we might have an easier<br />

chance of eliciting protective<br />

bnAbs by vaccination," the researchers<br />

noted.<br />

There is no doubt that cows'<br />

ability to produce bNAbs against a<br />

complicated pathogen like HIV in<br />

a matter of weeks, highlights even<br />

broader significance, particularly<br />

for emerging pathogens.<br />

Sok is an affiliate of IAVI's<br />

Neutralising Antibody Center a<br />

part of The Scripps Research Institute<br />

(TSRI) where multiple<br />

groups of scientists work collectively<br />

on an antibody-based HIV<br />

vaccine. Sources: IANS<br />

Red Cross Society trains 2,000 teachers in First Aid<br />

A THREE-DAY First Aid training<br />

workshop for basic school teachers<br />

in the Sekondi/Takoradi Metropolis<br />

has been held in Sekondi.<br />

The training is to equip them<br />

as active volunteers of the Ghana<br />

Red Cross Society to acquire<br />

knowledge in relief services and<br />

attend to emergency health situations<br />

in their schools and the communities.<br />

It was organised by the GRCS,<br />

in conjunction with the Ghana<br />

Education Service (GES) and attended<br />

by 72 teachers.<br />

The Western Regional Manager<br />

of the GRCS, Mr Matthew<br />

Boateng told the media on the<br />

sidelines of the training that 2,000<br />

teachers from 14 districts in the<br />

region had so far benefited from<br />

the training programme.<br />

Mr Boateng said as part of the<br />

training, the GRCS had supplied<br />

the teachers with First Aid Manuals<br />

to boost their capacity on how<br />

to deal with emergency health issues.<br />

He said every school and day<br />

care centre must have access to<br />

First Aid Kits to attend to school<br />

children in case of any casualties.<br />

Mr Boateng said most of the<br />

trained teachers had formed Disaster<br />

Management Teams<br />

through the Red Cross Society to<br />

prevent and mitigate disasters in<br />

their schools and communities.<br />

He said it was incumbent<br />

on first<br />

aiders "to adopt a<br />

life-saving technique<br />

to monitor the Airway,<br />

Breathing and<br />

Circulation (ABC) of<br />

an injured or sick<br />

person before a professional<br />

medical<br />

assistance.”<br />

He reminded the teachers<br />

that; "A good first aider to attend<br />

to ill people, disaster and<br />

accident victims, must be observant,<br />

resourceful, gentle,<br />

tactful, sympathetic, cheerful<br />

and courageous in a bid to<br />

bring relief to the situation".<br />

He said it was incumbent<br />

on first aiders "to adopt a lifesaving<br />

technique to monitor<br />

the Airway, Breathing and Circulation<br />

(ABC) of an injured<br />

or sick person before a professional<br />

medical assistance.”<br />

Mr Philip Bruce Arhin, the<br />

Regional First Aid Instructor,<br />

who took the teachers through<br />

First Aid steps, reminded them<br />

that as first aiders, they ought to<br />

make it their prime motive to<br />

“preserve lives, prevent a condition<br />

from getting worse, and promote<br />

recovery and human<br />

dignity".<br />

He appealed to the volunteers<br />

not to "frighten victims in emergency<br />

situations but encourage<br />

them that their condition will be<br />

better”.<br />

The trainees were taken<br />

through some basic steps such as<br />

cardio pulmonary resuscitation,<br />

external bleeding, wounds and<br />

cuts, bleeding with embedded object,<br />

shock, choking, drowning,<br />

burns, scalds and<br />

poisoning. GNA

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