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Joyce Browne studies high blood pressure in pregnant women Around the world, some 350,000 women die during childbirth, labor or the postpartum period every year. An important cause is high blood pressure during pregnancy. Research physician Joyce Browne wants to minimize this risk. High blood pressure in pregnancy can result in pre-eclampsia, which could put the health of mother and child at risk. Joyce conducts research among 800 women who are between 26 and 34 weeks pregnant. She wants to find out whether it is possible to predict which women benefit from giving birth as soon as possible when they are ill, and for which women delivery can be postponed. Every day in the womb gives the child a better start in life. Health of mother and child She performs a second study among 400 women a year after childbirth. She studies how many of them still have high blood pressure, as well as the general health status of mother and child. She compares the results with those of 100 women who had a normal childbirth. Joyce conducts the first study in Ghana, the second in Nigeria. Not because no pregnant women die from the effects of high blood pressure in the Netherlands, but because this happens far less frequently than in the African countries: 7 out of 100,000 live births, compared to 340 in Ghana and 814 in Nigeria. Solid healthcare structure The second reason for choosing these countries is that they have a solid healthcare structure. Most women visit a midwife at least once. Moreover, the hospitals are fairly well organized, so that Joyce can carry out her research there and improvements in healthcare can be implemented. Joyce works together with local doctors and researchers. She's had to adapt to their different cultural backgrounds, but also finds this very instructive. "There is more of a hierarchy and people are not as direct. That has made me more careful. I no longer say: 'I suggest we do this or this'. That's become: 'Would it be an idea if we did this or this?' Joyce expects to present the results of both studies in 2020. She doesn't yet know what she will do afterward: "But it will be a job in which I can continue to make a meaningful contribution to improving the health situation of women. This currently matches perfectly with conducting research." 36 Circulatory Health Magazine
Senior university lecturer Kerstin Klipstein-Grobusch Global Health: global insight into cardiovascular diseases Contributions to global health for everyone. That's the mission of the researchers at Julius Global Health. How? By performing clinical epidemiological research. By coming up with innovative solutions in healthcare technology. And by training new generations of professionals in healthcare. These are the words of senior university lecturer Kerstin Klipstein-Grobusch. "Global Health looks for new solutions in the prevention and treatment of diseases, such as cardiovascular diseases. Cardiovascular health is a key theme of Julius Global Health research. Does the development of babies and children affect their cardiovascular health as adults? What do we learn when we compare diabetes and cardiovascular disease and their risk factors internationally? And can we find ways to prevent cardiovascular diseases and diabetes in high- and low-income groups? These are the three questions on which cardiovascular research at Global Health centers. The researchers always take the life-cycle perspective as a basis: the development from fetus, baby and child into adult. In the strategic theme Circulatory Health heart and blood vessel health is a key theme. Our global target is research and education in the fields of diabetes and cardiovascular disease. Global Health researchers cooperate with local and international partners. Kerstin explains that there are ongoing projects all over the world aimed at preventing cardiovascular diseases and diabetes. "Global Health researchers are involved in studies in Asia/Pacific and Africa, where they work together with local and international partners. In Oxford, Sydney and other cities, they conduct research into the effects of gender differences on common risk factors for cardiovascular disease. Or into the relationship between ethnicity and the prevention of cardiovascular diseases. In the RODAM study of obesity and diabetes among African immigrants, researchers compare Ghanaians with their compatriots in Amsterdam, London and Berlin. This way, they find out more about the complex interaction between environment and genetics that plays a role in the development of type-II diabetes and obesity. Research projects in Asia are aimed at improving the quality of stroke care in an environment that is lacking resources. And a study in South-Africa targets changes in the risk of high blood pressure in the long term in rural and urban population groups." Circulatory Health Magazine 37
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