YSM Issue 90.4

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Welcome to Yale! The Yale Science and Engineering Association is here for you. Founded in 1914, the YSEA is one of the oldest university student/alumni organizations in the world with a focus on STEM. Whether near or far from New Haven, we help our members realize their goals and to connect in ways that strengthen the Yale science and engineering community. We are excited to be a part of your Yale journey, and we look forward to supporting you at Yale and beyond! Join us at: ysea.org
Yale Scientific Magazine VOL. 90 ISSUE NO. 4 CONTENTS OCTOBER 2017 NEWS 6 FEATURES 25 ON THE COVER 22 Rsearchers in the Herzon Lab at Yale have devised a total synthesis of the antibiotic pleuromutilin, opening the door to new potential antibiotics to help bacterial resistance 12 PUTTING THE PATCH ON RESISTANCE HOT, DENSE, AND SPINNING Just moments after the big bang, all matter existed in a state called the quark-gluon plasma. Yale professor Helen Caines and her group work with the STAR collaboration, together aiming to discover the properties of our universe this early in its history 15 THE SEARCH If cancer cells can’t find the highways of the body, they can’t spread and become more lethal. A mathematical model developed by Andre Levchenko and JinSeok Park of the Yale Systems Biology Institute provides a framework to expalin cell migration behavior that can be implemented down the line to keep cells searching longer. 18 IN SEARCH OF LOST TIME Yale researchers repair memory deficits in Alzheimer’s mice using a drug that targets abnormal protein interactions in the brain More articles available online at www.yalescientific.org 20 NANOPARTICLES FOR TRANSPLANTS Yale researchers develop a nanoparticle delivery system that releases siRNA capable of protecting ransplanted organs from rejcetion by the immune system. the nanoparticles have the potential to inhibit immune system’s recognition of transplants October 2017 Yale Scientific Magazine 3
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Page 5 and 6: F R O M T H E E D I T O R Reaching
Page 7 and 8: in brief NEWS The Twists and Turns
Page 9 and 10: neuroscience NEWS NOW YOU HEAR ME,
Page 11 and 12: public health NEWS NOT SO SWEET Met
Page 13 and 14: particle physics FOCUS distance, it
Page 15 and 16: THE SEARCH Mathematical model expla
Page 17 and 18: cell biology FOCUS ematical model w
Page 19 and 20: neuroscience FOCUS they were studyi
Page 21 and 22: molecular biology FOCUS However, if
Page 23 and 24: organic chemistry FOCUS key player
Page 25 and 26: genetics FEATURE NATURE AND NURTURE
Page 27 and 28: geology and geophysics FEATURE ΜIC
Page 29 and 30: low-density gas circling the galaxy
Page 31 and 32: molecular biology FEATURE a profess
Page 33 and 34: designed with attachments that bind
Page 35 and 36: INN VATI N STATION Decluttering our
Page 37 and 38: ALUMNI PROFILE SANDY CHANG (YC ‘8
Page 39: cartoon FEATURE BEFORE/AFTER ►BY

YSM Issue 90.4

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