YSM Issue 90.4
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Yale Scientific Magazine<br />
VOL. 90 ISSUE NO. 4<br />
CONTENTS<br />
OCTOBER 2017<br />
NEWS 6<br />
FEATURES 25<br />
ON THE COVER<br />
22<br />
Rsearchers in the Herzon Lab at<br />
Yale have devised a total synthesis<br />
of the antibiotic pleuromutilin,<br />
opening the door to new potential<br />
antibiotics to help bacterial resistance<br />
12<br />
PUTTING THE PATCH<br />
ON RESISTANCE<br />
HOT, DENSE, AND<br />
SPINNING<br />
Just moments after the big<br />
bang, all matter existed in a state<br />
called the quark-gluon plasma.<br />
Yale professor Helen Caines and<br />
her group work with the STAR<br />
collaboration, together aiming<br />
to discover the properties of our<br />
universe this early in its history<br />
15 THE SEARCH<br />
If cancer cells can’t find the highways<br />
of the body, they can’t spread and<br />
become more lethal. A mathematical<br />
model developed by Andre Levchenko<br />
and JinSeok Park of the Yale<br />
Systems Biology Institute provides a<br />
framework to expalin cell migration<br />
behavior that can be implemented<br />
down the line to keep cells searching<br />
longer.<br />
18<br />
IN SEARCH OF LOST<br />
TIME<br />
Yale researchers repair memory<br />
deficits in Alzheimer’s mice using a<br />
drug that targets abnormal protein<br />
interactions in the brain<br />
More articles available online at www.yalescientific.org<br />
20 NANOPARTICLES<br />
FOR TRANSPLANTS<br />
Yale researchers develop a nanoparticle<br />
delivery system that releases<br />
siRNA capable of protecting ransplanted<br />
organs from rejcetion by the<br />
immune system. the nanoparticles<br />
have the potential to inhibit immune<br />
system’s recognition of transplants<br />
October 2017<br />
Yale Scientific Magazine<br />
3
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