betty and guy beatty center for integrated - Inova Health System

D EPARTMENT OF ORTHOPAEDIC R ESEARCH
A NDERSON O RTHOPAEDIC R ESEARCH I NSTITUTE (AORI)
Working collaboratively with the Joint Replacement Center at Inova
Mount Vernon Hospital, the Anderson Orthopaedic Research Institute
(AORI) continues to generate clinically-relevant research related to hip
and knee joint replacements. The goal of this collaborative research is to
improve the quality of life for both current and future joint replacement
patients.
With every joint replacement innovation comes the need to determine
how the new technology affects clinical outcome. To evaluate new bearing
surfaces and implant designs, AORI is conducting several prospective,
randomized clinical trials. AORI also maintains an institutional joint
registry database that enables retrospective outcome analyses. In a
study that was published during the past year using this database, AORI
researchers found that a contemporary third-generation hip replacement
design significantly reduced the incidence periprosthetic bone loss
(known clinically as osteolysis) compared to a second-generation design
that had been used predominantly from 1990 through 2000.
AORI researchers also continue to publish clinical outcome studies related
to the use of porous-coated fixation for hip replacements, a technol-
ogy that was pioneered by Dr. Charles Engh at AORI over 30 years ago.
Among knee replacement patients, AORI is working to measure implant
wear and determine factors that influence the wear process. AORI is also
developing more sensitive techniques for quantifying outcomes after knee
replacement. These techniques, including analyses of patient gait and balance,
provide objective outcome data enabling improved comparisons of
implant designs.
Recognizing that joint replacement patients now routinely expect 20 to 30
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on understanding the mechanisms that lead to long-term implant failure,
including wear and bone loss. Using three-dimensional imaging modalities,
like computed tomography (CT), AORI is working to improve the diagnosis
and treatment of bone loss around joint replacements.
To ensure that their research findings are available to the world-wide orthopaedic
community, AORI-affiliated physicians publish their studies in
medical journals and present their findings at national and international
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publications in peer-reviewed orthopaedic journals. In addition, 32 talks
and two posters were presented at major scientific meetings
BOOKS, BOOK CHAPTERS AND JOURNAL ARTICLES
1. Egawa H, Powers CC, Beykirch SE, Hopper RH Jr, Engh CA Jr, Engh
CA Sr. Can the Volume of Pelvic Osteolysis be Calculated without
Using Computed Tomography? Clinical Orthopaedics and Related
Research. Published January 2009;;467:181-187
2. Engh CA Jr, MacDonald SJ, Sritulanondha S, Thompson A, Naudie
D, Engh CA Sr. Metal Ion Levels After Metal-on-Metal Total Hip Ar
throplasty: A Randomized Trial Clinical Orthopaedics and Related
Research. Published January 2009;;467:101-111
3. Rao AN, Engh JA, Engh GA, Parks NL. Mechanical Stability of Well-
Functioning Tibial Baseplates from Postmortem-Retrieved Total
Knee Arthroplasties. Journal of Arthroplasty Published February 2009
[Epub ahead of print]
4. Egawa H, Ho H, Hopper RH Jr, Engh CA Jr, Engh CA Sr. Computed
Tomography Assessment of Pelvic Osteolysis and Cup-Lesion Inter
face Involvement with a Press-Fit Porous-Coated Acetabular Cup.
Journal of Arthroplasty Published February 2009;;24(2):233-239
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