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No. 104 - Miljøstyrelsen

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LOAEL corresponds to the Danish occupational threshold limit value<br />

mentioned above. Corrected for long-term exposure 8<br />

(from working<br />

environment to normal population) the LOAEL becomes 0.009 mg Hg/m 3<br />

(9<br />

µg Hg/m 3<br />

). These values are based on adverse effects such as tremor and<br />

memory loss.<br />

Agency for Toxic Substances Disease Registry (ATSDR) set in 1999 a<br />

minimum risk level (MRL) of 0.0002 mg Hg/m 3 (0,2 µg Hg/m 3 ). In addition,<br />

TSDR has recommended concentration limits after cleaning and spillage<br />

indoors (ATSDR, 1999).<br />

In 2005 EPA in California established a long-term Reference Exposure Level<br />

(REL) of 0.00003 mg Hg/m 3 (0.03 µg Hg/m 3 ) on the basis of a LOAEL of<br />

0.025 mg Hg/m 3 (25 µg Hg/m 3 ) in the working environment (OEHHA,<br />

2008). An adjustment to normal population exposure gave a LOAEL of<br />

0.009 mg Hg/m 3 (9 µg Hg/m 3 ) (corresponds to USEPA above). This was<br />

converted to REL by using larger (un)certainty factors than those used by<br />

USEPA:<br />

� An (un)certainty factor of 10, due to the fact that it is not a NOAEL,<br />

� An (un)certainty factor of 30 for particular sensitivity of children,<br />

variation between individuals and for sensitivity of nervous system<br />

under development.<br />

CalEPA has furthermore set a limit value of 0.0018 mg/m 3<br />

exposure of one hour (Groth, 2008).<br />

(1.8 µg/m 3<br />

) for an<br />

A new Canadian assessment assumes a LOAEL value of 0.006 mg Hg/m 3 (6<br />

µg Hg/m 3 ). With an (un)certainty factor of 100 for uncertainty and modifying<br />

factors the result is a REL of 0.00006 mg Hg/m 3 (0,06 µg Hg/m 3 )<br />

(Richardson et al., 2009).<br />

A summary of information about limit values long-term mercury exposure is<br />

given in Table 4-2.<br />

8<br />

I.e. multiplied by a factor 5/7 to take into account all seven days of the week and not<br />

only five workdays, and a factor 10/20 to take into account a respiratory volume of 10<br />

for a workday and 20 m 3<br />

for 24 hours.<br />

m 3<br />

41

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