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Baby & Toddler

Health & Medical Diary

Dr Livia Chow Huey Ling

Consultant Paediatrician & Neonatologist,

Pantai Hospital Ayer Keroh

What is MIS-C?

MIS-C is a severe but rare complication

of COVID-19 infection where different

organs in the body get inflamed. For

example, the brain, heart, eyes, lungs,

kidney, skin and digestive tracts.

MIS-C usually occurs in older children

between 8 to 11 years old. However,

cases occurring in younger and older

children have also been reported.

Causes of MIS-C

The exact cause as to why MIS-C

occurs is not yet fully understood,

and to date, it is being continuously

studied. It is believed that it is caused

by an overactive immune response to

the COVID-19 virus and thus results in

inflammation and damage to various

organs in the body.

Symptoms to be

aware of

What are the symptoms that parents

should look out for if they suspect that

their child might have MIS-C? There

is a variable presentation of MIS-C in

children, and each child might not

have the same symptoms. Common

symptoms include:

• Persistent fever lasting between 3 to

5 days

• Tummy pain

• Vomiting

• Diarrhoea

• Skin rash

• Feeling lethargic

• Heart palpitations

• Red eyes

• Swollen hands or feet

• Swollen lips or tongue

• Headache

• Swelling of lymph nodes

Warning signs that indicate a more

serious condition are:

• Trouble breathing

• Severe tummy pain

• Difficult to wake your child up

• Pale or bluish discolouration of the

lips or skin

• Child appears confused

If your child develops any warning signs

or appears very sick, bring your child

to the hospital immediately. Similarly, if

your child has any of the above MIS-C

symptoms, please consult your doctor

immediately for further advice.

Doctors will need to perform several

tests, such as a COVID-19 test, some

blood work to look for evidence of

inflammation in the body to detect any

organ impairment and to look for other

causes besides MIS-C that can present

with similar presentations. Depending

on the symptoms that the child

presents with, there might be a need

for a chest X-ray and a heart scan.

Treating MIS-C

Children diagnosed with MIS-C will

usually need hospitalisation, and some

may require treatment and closer

observation in the Paediatric Intensive

Care Unit (ICU). Treatments will

include medication that reduces the

body’s excessive immune response and

medication that reduces inflammation

in the body. Other treatment and

support will be given depending on

the condition of the child as well as

test results. Most children recover from

MIS-C if detected and treated early.

From January to March this year,

we see more children infected with

COVID-19 and more of these children

are presenting with more serious

symptoms that need care in the PICU.

The best way to prevent complications

of COVID-19 infection, which includes

MIS-C, is to prevent COVID-19 infection

in the first place. Thus, it is crucial to

maintain strict preventative measures.

It is also advisable for children above

five years old to get the COVID-19

vaccination to protect against

COVID-19 infection. Above all, we

should not let our guard down as we

prepare to enter the endemic phase.

24 BabyTalk | May 2022

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