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Crucell corporate brochure (PDF)

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40<br />

<strong>Crucell</strong>’s commitment to the world – Taking responsibility<br />

Performance<br />

The P-category we call ‘Performance’ embraces four social responsibilities<br />

that we see as being central to our core business and our mission:<br />

innovation, saving lives, responsible supply chain management and<br />

transparency, by which we mean the responsibility to evaluate and<br />

report on our CSR activities in a comprehensive and systematic way.<br />

Transparency is, of course, an overarching principle in our CSR program<br />

and applies equally to all categories in the 4P policy framework.<br />

We have chosen to include it in the category most closely allied with<br />

our core business because we see transparency as a tool for strategic<br />

decision making, as well as a key responsibility towards our<br />

stakeholders. As a company dedicated to making a meaningful<br />

difference to people’s lives, we want the fullest possible understanding<br />

of our impact on society and our planet.<br />

Under the leadership of the Performance P-owner, whose function in the<br />

organization is Director Global Procurement, a large number of <strong>Crucell</strong><br />

employees have contributed to the gathering and analysis of information<br />

relevant to the initial set of key performance indicators (KPIs), targets<br />

and ambitions that were defined for this P-category in 2010 (see table 2).<br />

The P-owner’s expertise in the field of Procurement was especially<br />

valuable for developing a strategy for responsible supply chain<br />

management, which is one of five KPIs for which we have set<br />

particularly ambitious objectives.<br />

Besides a responsible supply chain, the other KPIs we have selected to<br />

measure our contribution in the Performance category are: prevention<br />

of illness and deaths, the number of pipeline products, research and<br />

development (R&D) expenses, animal welfare, CSR management<br />

improvement, and transparency objectives (relating to benchmarks<br />

such as the Dow Jones Sustainability Index, the Carbon Disclosure<br />

Project and the Transparency Benchmark). These indicators form the<br />

basis of the following discussion of activities and outcomes in the<br />

Performance category during 2010.<br />

1 Figures based on <strong>Crucell</strong>’s top 5 vaccines Quinvaxem®, Hepavax-Gene®, Epaxal®, Vivotif®<br />

and Inflexal® V. Total 101,666,000 doses minus 2% waste (2,033,320 doses) = 99,632,680<br />

doses sold in 2010 / 525600 minutes in 2010 = 189.5598 doses administered per minute.<br />

2 Figure based on <strong>Crucell</strong>’s top five vaccines in terms of sales volumes:<br />

Quinvaxem®, Hepavax-Gene®, Epaxal®, Vivotif® and Inflexal® V.<br />

www.crucell.com<br />

Saving lives<br />

During 2010, <strong>Crucell</strong> delivered 105 million doses of vaccines to people<br />

around the world, with the majority going to infants in developing<br />

countries. Together, the vaccines we have on the market prevent<br />

twelve major infectious diseases: childhood infections, travel and<br />

endemic illnesses, and respiratory disease. Allowing for the fact<br />

that some vaccines inevitably go to waste, we can estimate that<br />

a <strong>Crucell</strong> vaccine was given to 190 individuals every minute during<br />

2010 1 —a thought that makes us proud.<br />

However, we believe that the best measure of our impact on global<br />

health is not the number of doses we supply, but the number of deaths<br />

and cases of disease we prevent each year. In other words, how many<br />

people would have become sick or died if they had not received our<br />

vaccine? This can be estimated by combining sales figures with data<br />

on vaccine efficacy (how well a vaccine works), disease incidence<br />

(the expected number of new cases in a population) and case fatality<br />

(the death rate among infected patients).<br />

Based on the best available evidence for these parameters, and<br />

assuming a 2% vaccine waste rate, <strong>Crucell</strong>’s ‘top-five’ vaccines prevented<br />

more than 3.6 million cases of infectious disease and 809,823 deaths in<br />

2010 2 . This was similar to our health impact in 2009, when we prevented<br />

more than 3.6 million cases of disease and over 819,000 deaths.<br />

We did not meet our target of continuous improvement in the prevention<br />

of illness and deaths, as overall product sales were slightly lower in<br />

2010 than 2009. Higher sales of travel and endemic vaccines were more<br />

than offset by lower sales of our seasonal influenza vaccine (due to the<br />

limited availability of flu antigen and weaker overall demand) as well<br />

as the temporary suspension of Quinvaxem® shipments, as explained<br />

on page 46.

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