Master of Pharmacy - Nagpur University

17. J. Swarbrick, 2007. Encyclopedia of Pharmaceutical Technology, Third Edition,
Volume 1-6, Informa Healthcare.
18. R. Sheskey and Quinn, “Pharmaceutical excipients” Pharmaceutical Press.
19. M. Chaubal, “Excipients development for. Pharmaceutical, Biotechnology, and Drug
Delivery System”. Informa Healthcare.
20. S.C. Sweetman. Martindale-The complete drug reference. 37 th Edition, Vol. A and B,
Pharmaceutical Press, UK.
Subject code: MPH-P4
Subject : ADVANCED PHARMACEUTICS
Practical: 8 hrs. /week
1. Preformulation studies on tablets.
2. To study the decomposition kinetics of any three drugs.
3. To study the effect of copper ions on the ascorbic acid stability in solution
4. To determine the aqueous solubility of given drug sample at various temperature and
report its thermodynamic parameters.
5. To study the dissolution kinetics of given drug.
6. To study the effect of pH (2, 4, 6 and 8.0) on the apparent partition coefficient of a drug
in n-octanol- water buffer system.
7. To study the dissolution kinetics of immediate and extended release dosage form (any
five).
8. To study the effect of temperature on rheological behavior of poloxamers.
9. To study the effects of pH on rheological characteristics of carbopol gels using
Brookfield viscometer.
10. To determine the best compatible additive for aspirin tablets using at least five known
tablet components.
11. To study the diffusion of drug from topical gel using Franz diffusion cell.
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