Master of Pharmacy - Nagpur University

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RECOMMENDED BOOKS 1. M. Rowland, T.N. Tozer, 2011. “Clinical Pharmacokinetics and Pharmacodynamics: Concept and Applications”, 4 th Ed. Lippincott, Williams and Wilkins. 2. L. Shargel, S. Wu-Pong, B. C Andrew, 2005. “Applied Biopharmaceutics and pharmacokinetics”, Fifth Ed. McGraw-Hill Medical Pub. Division. 3. M. Gibaldi and D. Perrier, Second Edition. 1982. “Pharmacokinetics”. M. Dekker. 4. B.N. La Du, H. G. Mandel & E. L. Way, 1972. “Fundamental of drug metabolism and disposition”. Williams & Wilkins, Baltimore. 5. T.Z. Csaky, 1975. “Intestinal absorption and malabsorption”. Raven Press. 6. S. Niazi, 2007. “Handbook of Bioequivalence testing”. Informa Health Care. 7. D.J. Cutler, “Pharmaceutical Product Development: In vitro-In vivo Correlation”. Informa Health Care. 31
Syllabus Prescribed for Degree of Master of Pharmacy in Pharmaceutical Chemistry Semester-I Advanced Analytical Techniques (MC-S1 & MC-P1) Syllabus is same as prescribed Research Methodology and Biostatistics (MC-S2) for these papers for M. Pharm semester-I examination in Drug Regulatory Affairs (MC-S3) Pharmaceutics Subject code: MPC-S4 Subject: ADVANCED PHARMACEUTICAL CHEMISTRY-I THEORY: 60 Hours (4 hrs. /week) 1. Various Reaction Mechanisms: a. Substitution Reaction: Nucleophilic substitution reaction in aliphatic systems, SN1, SN2 reactions, Hydride transfer reaction, Cram‟s rule, Participation of neighbouring group in nucleophilic substitution reaction and rearrangements. Aromaticity, electrophilic and nucleophilic substitution in aromatic systems, Reactivity, orientation in electrophilic substitution. b. Elimination Reaction: Beta Elimination reactions, E1, E2 and E1cb mechanisms, Hoffman and saytzeff‟s rule for elimination, stereochemistry of E2 reaction, Elimination from alicyclic compounds. c. Addition Reaction: Electrophilic and Nucleophilic additions, Stereochemistry involved, Markonikov‟s rule. d. Free Radical Reaction: Formation, Detection, Reactions, Homolysis and free radical displacements, addition and rearrangements of free radicals. 2. Esterification reactions and ester hydrolysis. 3. Heterocylic chemistry: Nomenclature, synthesis, physical, chemical and spectroscopic properties of pyrrole furan, thiophen, pyridine, pyridazine, pyrimidine, pyrazine, quinoline, isoquinoline, indole, oxazole, imidazole and benzimidazole. 4. Oxidation and reduction reactions: Oxidation reaction involving use of potassium permanganate, potassium dichromate, chromic acid, selenium dioxide, periodic acid, N-bromo succinimide and oppenaure oxidation. Reduction reactions using metal and acid, metal amine reduction, catalytic reduction, hydrogenation of double bond, triple bond and aromatic rings, birch reduction, Meerwein-Pondroff-Verley reduction. 5. Modern synthetic methods: a) Green Synthesis: Introduction; Green reagents; green catalysts; ionic solvents; phase transfer catalysis in green synthesis; application of phase transfer catalysts in green synthesis of heterocyclic compounds: Williamson‟s synthesis, Wittig reaction. 32
Page 1 and 2: Rashtrasant Tukadoji Maharaj Nagpur
Page 3 and 4: have been allocated for seminar. Ma
Page 5 and 6: The marks will be given in all exam
Page 7 and 8: SCHEME OF TEACHING AND EXAMINATION
Page 9 and 10: Pharmacology APPENDIX-C Semester Pa
Page 11 and 12: Biotechnology APPENDIX-E Semester P
Page 13 and 14: Industrial Pharmacy APPENDIX-G Seme
Page 15 and 16: Clinical Pharmacy APPENDIX-I Semest
Page 17 and 18: Pharmaceutical Management APPENDIX-
Page 19 and 20: RECOMMENDED BOOKS: 1. Skoog, DA, Ho
Page 21 and 22: 6. C.R. Kothari, 2004. “Research
Page 23 and 24: Study of newer excipients like cycl
Page 25 and 26: Semester-II Subject code: MC-S7 Sub
Page 27 and 28: 6. S. K. Gupta, Drug screening meth
Page 29 and 30: 8. Protein & peptide drug delivery
Page 31: Semester-III Subject code: MPH-S13
Page 35 and 36: Semester-II Validation & CGMP (MC-S
Page 37 and 38: 4. RECENT ADVANCES IN FOLLOWING CAT
Page 39 and 40: Semester-III Subject code: MPC-S13
Page 41 and 42: Syllabus prescribed for Degree of M
Page 43 and 44: Subject code: MPL-P4 Subject: ADVAN
Page 45 and 46: RECOMMENDED BOOKS: 1. Goodman and G
Page 47 and 48: 5. Koda and Kimble, Hand book of Ap
Page 49 and 50: 2. To measure blood pressure using
Page 51 and 52: 4. Craig, C.R. and Stitzel, B.E.; M
Page 53 and 54: 6. Chaudhari R.D., Herbal Drug Indu
Page 55 and 56: Subject code: MPG-S10 Subject: HERB
Page 57 and 58: Semester-III Subject code: MPG-S13
Page 59 and 60: 5. Joe Sambrooke, 2001. Molecular c
Page 61 and 62: Subject code: MBT-S10 Subject: FERM
Page 63 and 64: Semester-III Subject code: MBT-S13
Page 65 and 66: 4. Current Good Manufacturing Pract
Page 67 and 68: 7. P. P. Sharma. Cosmetics- Formula
Page 69 and 70: Semester-III Subject code: MQA-S13
Page 71 and 72: 6. King and Turco, Sterile Dosage F
Page 73 and 74: 3. Leon Lachmann. Pharmaceutical Do
Page 75 and 76: Subject code: MIP-P9 Subject: ADVAN
Page 77 and 78: Semester-I Syllabus Prescribed for
Page 79 and 80: Subject code: MPI-P4 Subject: INFOR
Page 81 and 82: concept of homology modeling potent
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4. Alberts, B., Bray ,D., Lewis J.,
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targets (from bioinformatics method
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7. Avery‟s Drug Treatment, 4 th E
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RECOMMENDED BOOKS : 1. Roger and Wa
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Subject code: MCP-P10 Subject: CLIN
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5. Practice Standards & Definitions
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5. G.E. Trease and W.C. Evans., Pha
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14. Toms, G., Marine Pharmacognosy
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Subject code: MNP-P10 Subject: STAN
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Syllabus prescribed for Degree of M
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Semester-II Validation & CGMP (MC-S
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Subject code: MPM-P9 Subject: PHARM
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Elective Subjects: Group A: Pharmac
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Subject code: MPHE2 Subject: FERMEN
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7. Hospital drug policy Pharmacy an
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Validation, Computer System Validat
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GROUP B: PHARMACEUTICAL CHEMISTRY S
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Subject code: MPCE3 Subject: COMBIN
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Subject code: MPCE5 Subject: ORGANI
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GROUP C: PHARMACOLOGY, CLINICAL PHA
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Subject code: MPLE3 Subject: IMMUNO
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10. Neurological disorders. 11. Tec
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GROUP D: PHARMACOGNOSY, NATURAL PRO
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3. Profiles for commercial cultivat
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RECOMMENDED BOOKS: 1. Textbook of I
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Subject code: MQAE2 Subject: HUMAN
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4. Specifications and quality: mate
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Setting a goal for the control subj
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Master of Pharmacy - Nagpur University

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