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The Poor Responder – New Medical Treatment Poor Responders ...

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2<br />

How do we define a poor responder<br />

� AGE<br />

� CLINICAL<br />

� No of follicles : 1 - 4 , No of oocytes : 1 - 4<br />

� Peak Estradiol levels: < 500 pg/ml<br />

� Excessive requirements of gonadotropins: > 450 IU<br />

� TESTS<br />

� Basal day 3 FSH<br />

� CC challenge test<br />

� Inhibin B<br />

� AMH<br />

� Ovarian Volume<br />

� Antral follicle count<br />

Evaluation and management of low<br />

responders in IVF - reviews<br />

�� Evaluation and <strong>Treatment</strong> of Low <strong>Responder</strong>s in Assisted Reproductive Reproductive<br />

Technology<br />

SOZOS J. FASOULIOTIS, ALEX SIMON, and NERI LAUFER<br />

Journal of Assisted Reproduction and Genetics, Vol. 17, No. 7, 2000<br />

� Clinical management of low ovarian response to stimulation for IVF: a systematic review<br />

B.C.Tarlatzis1, L.Zepiridis, G.Grimbizis and J.Bontis<br />

Human Reproduction Update, Vol.9, No.1 pp. 61±76, 2003<br />

� Interventions for ’poor responders’ to controlled ovarian hyperstimulation (COH) in invitro<br />

fertilisation (IVF) (Review)<br />

Shanbhag S, Aucott L, Bhattacharya S, Hamilton MA, McTavish AR<br />

<strong>The</strong> Cochrane Library 2007, Issue 3

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