The Poor Responder – New Medical Treatment Poor Responders ...
The Poor Responder – New Medical Treatment Poor Responders ...
The Poor Responder – New Medical Treatment Poor Responders ...
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32<br />
�� No advantage for letrozole/antagonist protocol<br />
�� Increased follicular fluid androgens may have<br />
negative effect on oocyte quality<br />
Frattarelli, J et al, Fertility sterility 2007<br />
�� Retrospective paired study of 60 women, treated with<br />
traditional protocol and luteal estradiol protocol in<br />
consecutive cycles<br />
�� 44 women traditional first, 16 women luteal estradiol first<br />
�� Same protocol both cycles <strong>–</strong> microdose flare or GnRH<br />
antagonist PLUS estradiol<br />
�� fresh IVF cycles only<br />
�� Pregnancy outcome rates not indicative as no women<br />
became pregnant in first cycle<br />
�� Main outcome measure <strong>–</strong> number of embryos with >7<br />
cells on day 3
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