The Poor Responder – New Medical Treatment Poor Responders ...
The Poor Responder – New Medical Treatment Poor Responders ...
The Poor Responder – New Medical Treatment Poor Responders ...
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24<br />
Frattarelli, J et al, Fertility sterility 2007<br />
�� Retrospective cohort study of 1250 poor-<br />
responder women undergoing IVF<br />
�� Aspirin<br />
→ decreased platelet production of PGG<br />
→ lower level of Thromboxane<br />
→ vasodilation, increased blood flow in ovarian<br />
arteries<br />
→ improved quality of oocytes, higher<br />
implantation, pregnancy and live-birth live birth rates<br />
�� Step down protocol<br />
�� 417 women were treated with 81mg<br />
aspirin beginning during month prior to IVF<br />
cycle<br />
833 underwent standard protocol only