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NASA Scientific and Technical Aerospace Reports

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20040046869 Institute of Space Medico-Engineering, Beijing, China<br />

Effect of Microwave Irradiation on ATPase Activity <strong>and</strong> Voltage Dependent Ion Channel of Rat Hippocampus Cell<br />

Membrane<br />

Zhao, Ya-Li; Ma, Hong-Bo; Song, Jin-Ping; Yang, Yu-Hua; Pu, Jing-Sui; Zheng, Jian-Quan; Space Medicine <strong>and</strong> Medical<br />

Engineering, Volume 16, No. 1; February 2003, pp. 36-40; In Chinese; See also 20040046857; Copyright; Avail: Other<br />

Sources<br />

The objective of this research is to study the effect of microwave irradiation on hippocampus cell. Changes of ATPase<br />

activity <strong>and</strong> voltage dependent ion channel of hippocampus cell membrane were observed in mice exposed to 2 450 MHz<br />

microwave irradiation of 10 milliwatts per square centimeters from a physical therapy machine. Histochemical method <strong>and</strong><br />

patch clamp method were used to determine the activity of Na(+), K(+) -ATPase, Ca(2+), Mg(2+) -ATPase <strong>and</strong> voltage<br />

dependent Na(+), K(+), Ca(2+) channels respectively. 1) Na(+), K(+) -ATPase activity of microwave irradiated mice showed<br />

no significant change as compared with the control, but the activity of Ca(2+), Mg(2+) -ATPase decreased significantly (P less<br />

than 0.05); 2) In microwave irradiated mice, Na(+), K(+), Ca(2+) current inducement rate in hippocampus neuron decreased<br />

significantly, the membrane voltage of Na(+) current peak shifted to depolarization, <strong>and</strong> the attenuation rate of Na(+) current<br />

<strong>and</strong> current A inducement rate decreased significantly as compared with control mice. Irradiation of 2 450 MHz microwave<br />

at a doze of 10 milliwatts per square centimeter was not fatal to mice hippocampus cell. But Ca(2+), Mg(2+) -ATPase activity<br />

of hippocampal cell membrane <strong>and</strong> voltage dependent Na(+), K(+), Ca(2+) ion channel of hippocampal nervous were affected<br />

which would affect study <strong>and</strong> memory.<br />

Derived from text<br />

Hippocampus; Irradiation; Microwaves; Rats; Cell Membranes (Biology); Electric Potential; Ion Channels (Biology)<br />

20040046870 Institute of Space Medico-Engineering, Beijing, China<br />

Analysis of Heat Transfer in Skin Tissues Subjected to Hot Water<br />

Jiang, Shi-chen; Li, He-jie; Ma, Ning; Zhang, Xue-xue; Space Medicine <strong>and</strong> Medical Engineering, Volume 16, No. 1;<br />

February 2003, pp. 44-47; In Chinese; See also 20040046857; Copyright; Avail: Other Sources<br />

The objective of this research is to analyze heat transfer process in skin tissues subjected to hot water <strong>and</strong> thus to predict<br />

the extent of scald. Based on Pennes’ Bio-heat Equation, a model for characterizing the damage process in tissues was<br />

presented <strong>and</strong> used for its analysis. Temperature distribution in the tissues during the process <strong>and</strong> the time of beginning of scald<br />

were numerically obtained. It was found that the effects of different initial temperature distribution, convection coefficients<br />

between the hot water <strong>and</strong> the tissue surfaces, <strong>and</strong> the temperature of the hot water are significant. The transient heat transfer<br />

behavior in multi-layer tissues subjected to hot water can be predicted by the present model. It is useful in the clinical<br />

diagnosis <strong>and</strong> therapy for the scald caused by hot water.<br />

Derived from text<br />

Heat Transfer; Mathematical Models; Tissues (Biology); Skin (Anatomy); <strong>Aerospace</strong> Medicine; Water Temperature; Hot<br />

Surfaces<br />

20040046871 Tsinghua Univ., Bejing, China<br />

Development of Data Acquisition Card in Exercise-ECG Detection System<br />

Sun, Yang; Shen, Yong-lin; Xie, Hong-tao; Space Medicine <strong>and</strong> Medical Engineering, Volume 16, No. 1; February 2003,<br />

pp. 64-67; In Chinese; See also 20040046857; Copyright; Avail: Other Sources<br />

The objective of this research is to develop a data acquisition card in exercise-ECG detection system that can gather<br />

multi-channel exercise-ECG signals simultaneously <strong>and</strong> precisely. 1) In hardware, the card was based on 196 KC single-chip<br />

microprocessor which can gather signals, process data <strong>and</strong> control circuit; 2) In software, single-chip microprocessor<br />

completed the following three main tasks: the A/D conversion, signal processing <strong>and</strong> communication with computer. The main<br />

computed receives the data <strong>and</strong> performs real time data processing. The data acquisition card in exercise-ECG detection<br />

system cooperates with the main CPU. In order to release the main CPU, the card realizes the data pre-processing <strong>and</strong> makes<br />

reasonable uses of the hardware resource. The data acquisition card could meet the needs of clinical detection of<br />

exercise-ECG.<br />

Author<br />

Data Acquisition; Detection; Electrocardiography; Physical Exercise; Punched Cards; <strong>Aerospace</strong> Medicine; Chips<br />

(Electronics)<br />

144

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