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“Crowd Control” Turning Cells into Organs via Collective Migration

“Crowd Control” Turning Cells into Organs via Collective Migration

“Crowd Control” Turning Cells into Organs via Collective Migration

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What is it?<br />

The zebrafish lateral line: an in vivo model for collective migration<br />

Transgenic : mGFP fused to claudin B promoter (cldnb:gfp)<br />

Mechanosensory hair cell organs deposited by migrating epithelium (RG Harrison, 1906).<br />

Top view, 10x/0.25 NA<br />

frame every 4 mins<br />

multi-tasking - cells migrate, grow, divide, differentiate and change shape simultaneously.<br />

“Embryogenesis in a nutshell” or “An animal inside an animal”

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