NEWS | <strong>IMS</strong> ONCOLOGY EXPERTISE The <strong>IMS</strong> HEOR Bibliography captures more than 2200 research publications with a history of 25 years across all key therapy areas. Oncology is one of our leading fields of research. Oncology is a key research area for <strong>IMS</strong> HEOR The oncology market is experiencing spectacular growth and unprecedented innovation. It is predicted to become the largest single therapy sector in value terms by 2015 – worth US$75 billion. New molecular targeted therapies, diagnostics, genomics and proteomics are changing the face of cancer treatment, spurring exciting opportunities - and also new challenges - for this healthcare sector worldwide. The <strong>IMS</strong> HEOR global team has completed projects on 20 different tumor types, spanning all aspects of health economics and outcomes research, with particular emphasis on health economic modeling and retrospective outcomes research. The top ten cancers we have covered are: 1. Breast 2. Lung [NSCLC/SCLC] 3. Colorectal 4. Lymphoma 5. Melanoma/BCC 6. Prostate 7. Multiple myeloma 8. Leukemias [CLL/CML] 9. Mesothelioma 10. Cervical <strong>IMS</strong> HEOR ONCOLOGY PROJECTS SPAN ALL ASPECTS OF HEOR 43% ONCOLOGY IS A LEADING AREA OF <strong>IMS</strong> HEOR EXPERTISE 116 107 PAGE 4 <strong>IMS</strong> HEALTH ECONOMICS & OUTCOMES RESEARCH 150 233 259 330 Diabetes Oncology Cardiovascular Mental health HE modeling Prospective outcomes research Neurological disorders 14% 30% 13% Retrospective outcomes research Value communications Respiratory diseases
<strong>IMS</strong> HEOR Bibliography <strong>Health</strong> economics review of bowel cancer in Australia NSW Cancer Institute, 2008, Sydney, Australia (Review) Bishop J, Glass P, Tracey E, Hardy M, Warner K, Makino K, Gordois A, Wilson J, Guarnieri C, Feng J, Sartori L Economic model of granulocyte -colony stimulating factor (G-CSF) in primary (PP) and secondary prophylaxis (SP) of febrile neutropenia (FN) in Non-Hodgkin's Lymphoma (NHL) patients undergoing chemotherapy in France ISPOR 14th Annual European Congress, Madrid, Spain, 5-8 November, 2011 Perrier L, Sebban C, Leon N, Maurel F, Cohen-Nizard S, De Liège F <strong>IMS</strong> ONCOLOGY EXPERTISE | NEWS Our research expertise and therapy area knowledge are captured in more than 200 publications each year, spanning virtually all therapy areas and 50+ countries worldwide. Contact <strong>IMS</strong> (details on back cover) for a copy of the latest <strong>IMS</strong> HEOR Bibliography of published papers (2008-2012) or visit www.imsheorbibliography.com to explore our database online. The <strong>IMS</strong> HEOR bibliography in oncology spans all key areas of health economics and outcomes research, including retrospective and observational analyses, budget impact, cost-effectiveness and cost utility modeling, model adaptations, epidemiology and burden of disease studies, indirect comparisons, and meta-analyses, bringing important new findings across all key tumor types and countries around the world. Breast cancer diagnostic process: Management and cost evaluation in Italy ISPOR 12th Annual European Congress, Paris, France, 24-27 October, 2009 Pantaleoni M, Marchese E Second-line therapy for non-small cell lung cancer (NSCLC): A retrospective cost analysis Tumordiagn u Ther, 2008; 29:211-217 Gatzemeier U, Pirk O, Gabriel A, Kotowa W, Heigener D Development of a co-morbidity scale in patients with chronic lymphocytic leukemia ISPOR 13th Annual European Congress, Prague, Czech Republic, 6-9 November, 2010 Carbonell F, De La Serna J, Giraldo P, Lopez A, Rios E, Perulero N, Castro-Gomez AJ Cost-effectiveness of cetuximab, bevacizumab, and panitumumab in first-line treatment of metastatic colorectal cancer (mCRC) for patients with KRAS wild-type (wt) tumors in the UK Journal of Clinical Oncology, 2011;29(Suppl):A16571 Samyshkin Y, Hertel N, Griebsch I Five-year routine cervical cancer screening rates and intervals in a United States health plan Current Medical Research and Opinion, 2008; 24(9):2429- 2435 Schabert VF, Ye X, Insinga RP, Singhal PK, Riedel AA Cost-utility analysis of dasatinib as a second-line treatment in the chronic phase of chronic myeloid leukaemia in Russia ISPOR 13th Annual European Congress, Prague, Czech Republic, 6-9 November, 2010 Kuznetzov SV, Mungapen L, Samyshkin Y, Jakouloff D, Sbarigia U, van Baardewijk M Economic evaluation in the treatment of advanced and/or metastatic gastric cancer from the perspective of the public health system in Mexico ISPOR 17th Annual International Meeting, Washington, DC, USA, 2-6 June, 2012 Lechuga D, Alva M, Salinas GE, Leyva V Epidemiologic study to assess patient involvement in choice of adjuvant chemotherapy in breast cancer (PROSA study) Clinical and Translational Oncology, 2009; 11(4):221-7 Tusquets I, Espinosa Arranz E, Méndez M, Gil JM, Guallar JL, Perulero N A retrospective analysis illustrating the substantial clinical and economic burden of prostate cancer Prostate Cancer and Prostatic Diseases, 2010; 13(2):162-167 Crawford ED, Black L, Eaddy M, Kruep EJ Risk of treatment failure after first-line sunitinib therapy in patients with metastatic renal cell carcinoma Journal of Clinical Oncology, 2012; 30 (Suppl 5): Abstract 438 Chen CC, Hess GP, Liu Z, Gesme DH, Agarwala SS, Hill JW, Guo MA ACCESSPOINT • VOLUME 2 ISSUE 4 PAGE 5