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Estudio de susceptibilidad in vitro

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Def<strong>in</strong>ición n <strong>de</strong> Puntos <strong>de</strong> Cortes<br />

Criterios generados para Candida spp por CLSI<br />

Criterios<br />

Fluconazol<br />

(µg / ml)<br />

Itraconazol<br />

(µg / ml)<br />

Flucitos<strong>in</strong>a<br />

Sensible < 8 < 0,125 < 4<br />

SDD 16 a 32 0,25 a 0,5<br />

Intermedio 8 a 16<br />

Resistente > 64 > 1 > 32<br />

• SDD: Sensibilidad Dosis Dependiente<br />

• Basado en candidiasis superficial (Flu e itra), <strong>in</strong>vasoras (Flu), datos históricos<br />

e <strong>in</strong>fección n animal (5FC)<br />

• Detecta resistencia y ayuda a <strong>de</strong>term<strong>in</strong>ar falla clínica<br />

14

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