Estudio de susceptibilidad in vitro

IFI in Chile: a multicenter study of fungal prevalence and susceptibility during a 1 year period.
Species (No.)
C. albicans (59) Amphotericin B
Fluconazole
Itraconazole
C. famata (6) Amphotericin B
Fluconazole
Itraconazole
C. glabrata (6) Amphotericin B
Fluconazole
Itraconazole
C. parapsilosis (23) Amphotericin B
Fluconazole
Itraconazole
C. tropicalis (15) Amphotericin B
Fluconazole
Itraconazole
C. neoformans (11) Amphotericin B
Fluconazole
Itraconazole
All yeasts* (125)
Antifungal agents MIC (µg/ml)(
Range 50% 90%
Amphotericin B
Fluconazole
Itraconazole
0.03-1
0.25-16
0.03-0.5
0.5
0.03-0.13
0.13
8-16
0.5-1
0.06-1
0.25-128
0.03-16
0.03-1
0.25-128
0.03-0.25
0.25
0.03-1
0.25-128
0.03-0.5
0.5
0.13-0.5
0.5
0.5-16
0.03-0.5
0.5
0.03-1
0.25-128
0.03-16
Cepas aisladas entre 2000 y 2001 (RED IFI en Chile)
0.06
0.25
0.03
0.03
8
0.5
0.5
8
0.5
0.13
1
0.03
0.06
0.5
0.06
0.25
2
0.13
0.13
0.5
0.03
1
1
0.06
0.13
16
1
1
128
16
0.25
4
0.13
1
128
0.5
0.5
8
0.25
1
16
0.5
% S - R
100 – 0
97 – 0
98 – 0
100 – 0
50 – 0
0 – 33
100 – 0
50 – 33
33 – 50
100 – 0
96 – 4
96 – 0
100 – 0
87 – 7
80 – 0
100 – 0
91 – 0
73 – 0
100 – 0
89 – 6
84 – 4
31
Silva et al., Med. Mycol. 42: 333-9, 2004