12.07.2015 Views

L'hybridation génomique comparative en microréseau d'ADN (HGCM)

L'hybridation génomique comparative en microréseau d'ADN (HGCM)

L'hybridation génomique comparative en microréseau d'ADN (HGCM)

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27 ADNs (Aicardi) + ADN référ<strong>en</strong>t – 244KOligos variants31 206 sondesFILTRESDye swapping FP 244K (IGR, témoin self/self) Algorithme5 459 variations441 FPRégions variantes(>3 sondes consécutives)214 régions : 19,3%11/lame <strong>en</strong> moy<strong>en</strong>neFILTRES: DGV et DECIPHEROligos variants(>3 pati<strong>en</strong>tes)288 variations récurr<strong>en</strong>tes5,3% du signalCOTATION: 1-4 (régions) et 1-3 (oligos)

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