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DIGAMI 2 - Azienda USL di Reggio Emilia

DIGAMI 2 - Azienda USL di Reggio Emilia

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GP IIb/IIIa Inhibitors Reduc e Mo rtality in Diabe tic<br />

Patients with non-ST Segment Elevation Acute<br />

Co ro nary S yndro mes<br />

30-Day Mortality Diabetic Patients PCI<br />

Trial N Odds Ratio & 95% CI Placebo IIb/IIIa<br />

PURSUIT<br />

457<br />

p=0.57<br />

3.3%<br />

2.4%<br />

PRISM<br />

PRISM-PLUS<br />

GUSTO IV<br />

PARAGON A<br />

PARAGON B<br />

Pooled<br />

147<br />

107<br />

239<br />

45<br />

284<br />

1279<br />

p=0.50<br />

p=1.00<br />

p=0.037<br />

p=0.31<br />

p=0.06<br />

p=0.002<br />

2.5%<br />

1.8%<br />

6.5%<br />

7.1%<br />

4.3%<br />

4.0%<br />

0.0%<br />

0.0%<br />

1.2%<br />

0.0%<br />

0.7%<br />

1.2%<br />

0 0.5 1 1.5 2<br />

Breslow-Day: p=0.46 IIb/IIIa Better Placebo Better<br />

Roffi. Circulation 2001;104:2767

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