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Terapia innovativa: oltre il PEB? Relatore: Dr ... - Oncologia Rimini

Terapia innovativa: oltre il PEB? Relatore: Dr ... - Oncologia Rimini

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Prognostic factors in relapsed or refractory germ-cell tumors<br />

ASCO 2009 - Abstr # 5030<br />

A. Lorch, J. Beyer , C. Mollevi, M. Guerra, A. Kramar for the International Group on<br />

Prognostic Factors in Relapsed or Refractory Germ-Cell Tumors<br />

METHODS:<br />

Between 09/2007 and 12/2008 data on 1984 pts with rr-GCT were collected<br />

from 38 centers/groups worldwide (participating centers see below).<br />

Inclusion criteria were as follows<br />

> germ cell tumor defined either by histology and/or by markers<br />

> first-line chemotherapy after January 01,1990<br />

> at least three cycles of cisplatin-based first-line chemotherapy<br />

> unequivocal relapse or progression after first-line chemotherapy<br />

> no previous salvage chemotherapy<br />

> first-salvage chemotherapy with either conventional-dose<br />

cisplatin-based treatment or with any high-dose regimen

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