Case report - Blood Transfusion
Case report - Blood Transfusion
Case report - Blood Transfusion
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M Waldner et al.<br />
naturally occurring and not an immune response.<br />
However, there are published <strong>report</strong>s of rare cases of<br />
D- negative males, not immunised by transfusions,<br />
with anti-D serum alloantibodies 4,5 .<br />
In any case, after having excluded what seemed<br />
probable and obvious, we can do nothing but accept<br />
the improbable and use Issitt's words related to the<br />
complex, still unresolved problems of the Rh system,<br />
"we can only add Amen" 6 .<br />
Acknowledgements<br />
We would like to thank Dr. Giorgio Assali for his<br />
precious advice and help with this manuscript and all<br />
the Staff of the Immunohaematology Laboratory of<br />
our <strong>Transfusion</strong> Service for their valuable work.<br />
Tuttavia l'esistenza di rari soggetti D- negativi di sesso<br />
maschile, non immunizzati da trasfusioni, che presentano<br />
nel siero alloanticorpi anti-D è riferita in letteratura 4,5 . In<br />
ogni caso, dopo aver escluso ciò che appariva probabile<br />
ed evidente, non possiamo che accettare ciò che appare<br />
improbabile, facendo nostre le parole di Issitt relative<br />
alle complesse problematiche ancora irrisolte del sistema<br />
Rh, "we can only add Amen" 6 .<br />
Ringraziamenti<br />
Desideriamo ringraziare il Dott. Giorgio Assali per<br />
i suoi preziosi consigli e l'aiuto nella stesura del<br />
manoscritto e tutto lo Staff del laboratorio di<br />
Immunoematologia del nostro Servizio Trasfusionale<br />
per il prezioso lavoro svolto.<br />
References<br />
1) Scott ML. Monoclonal anti-D for immunoprophylaxis. Vox<br />
Sang 2001; 81: 213-8.<br />
2) Bowman JM. RhD haemolytic disease of the newborn. N<br />
Engl J Med 1998; 339: 1775-7.<br />
3) Brecher ME (Editor in Chief). Technical Manual. 14th<br />
ed., Bethseda, MD, AABB; 2003.<br />
4) Contreras M, De Silva M, Teesdale P, Mollison PL. The effect<br />
of naturally occurring Rh antibodies on the survival of<br />
serologically incompatible red cells. Br J Haematol 1987;<br />
65: 475-8.<br />
5) Algora M, Barbolla L, Contreras M. Naturally occurring anti-<br />
D, anti-K, anti-Fy a and anti-Le ab . Vox Sang 1991; 61: 141.<br />
6) Issit PD. Applied <strong>Blood</strong> Group Serology, 3 rd ed, Montgomery<br />
Scientific Publications, Miami, FL;198<br />
160 <strong>Blood</strong> Transfus 2005; 3: 157-60