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From high phosphate and calcium to<br />
calcification<br />
• Originally tought to be passive process<br />
• Now:<br />
– Dysregulation of all sorts of metabolites<br />
by kidney<br />
damage<br />
– Combined with<br />
high phosphate<br />
and high calcium<br />
– Leads to active<br />
extra-osseous<br />
bone formation
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