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Vitamine D

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Paricalcitol vs. Calcitriol<br />

• 263 hemodialyse patiënten<br />

• primaire eindpunten:<br />

– reduceer plasma PTH tot 50% van de baseline.<br />

• Secondaire eindpunten:<br />

– hypercalcemie<br />

– verhoogd Ca x P product<br />

• Resultaten:<br />

– Geen lager pth<br />

– Geen beter Ca X P product<br />

– Geeft minder hypercalcemische episodes dan<br />

calcitriol<br />

Sprague et al. Kidney Int 2003; 63: 1483-90

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