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Lægemidler med virkning på respirationsvejene Astma

Lægemidler med virkning på respirationsvejene Astma

Lægemidler med virkning på respirationsvejene Astma

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Nye behandlinger for astma<br />

TH 1<br />

IFNγ<br />

IL-12<br />

TH2<br />

Immunomodulators<br />

-PDE inhibitors,<br />

-Glucocorticoids,<br />

-Cyclosporine<br />

Anti-IL-5 MAb<br />

Anti-IL-4, Anti-IL-13<br />

IL-4R<br />

Eosinophil<br />

B Cell<br />

Apoptosis<br />

-GCs<br />

-p38 MAP<br />

Inhibitors<br />

Airway<br />

Inflammation<br />

& BHR<br />

IgE<br />

Anti-IgE<br />

Omalizumab (Xolair)<br />

Monoklonalt humant antistof mod IgE<br />

Kun til behandling af svær allergisk astma<br />

Gives subkutant /2 uge<br />

Effekt?<br />

Pris!!!

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