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Full text PDF (6.1 MB) - Jurnalul de Chirurgie

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Articole Multimedia <strong>Jurnalul</strong> <strong>de</strong> <strong>Chirurgie</strong>, Iaşi, 2008, Vol. 4, Nr. 4 [ISSN 1584 – 9341]<br />

ADRENCORTICAL CARCINOMA<br />

ADJUVANT THERAPY<br />

ROLE of the MITOTANE<br />

p=0.7<br />

ADRENCORTICAL CARCINOMA<br />

ADJUVANT THERAPY<br />

ROLE of the MITOTANE<br />

Berruti at al Endocr Relat Cancer. 2005; 12(3): 657<br />

Etoposi<strong>de</strong>, doxorubicin and<br />

cisplatin plus mitotane in the treatment<br />

of advanced adrenocortical carcinoma: a large<br />

prospective phase II trial.<br />

NO effects in survival (p=0.7)<br />

…but…<br />

“Down-staging”<br />

Increase up the median survival (p

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