Full text PDF (3.9MB) - Jurnalul de Chirurgie
Full text PDF (3.9MB) - Jurnalul de Chirurgie
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Articole Multimedia <strong>Jurnalul</strong> <strong>de</strong> <strong>Chirurgie</strong>, Iaşi, 2008, Vol. 4, Nr. 2 [ISSN 1584 – 9341]<br />
Parathyroid Carcinoma<br />
Surgical<br />
Treatment<br />
Surgical<br />
Treatment<br />
Superior and inferior parathyroi<strong>de</strong>ctomy<br />
Ipsilateral hemithyroi<strong>de</strong>ctomy<br />
Thymectomy<br />
Lympha<strong>de</strong>nectomy when necessary<br />
Case n. 24<br />
Favia, , W J S 1998<br />
22<br />
Parathyroid Carcinoma<br />
Adjuvant therapies<br />
Palliative: control of hypercalcemia<br />
Chemotherapy: sporadic attempts useful<br />
only for palliation<br />
Radiotherapy: ( 67 Ga, external RT)<br />
Only some sporadic cases<br />
of efficacy reported Wynne 1992<br />
San<strong>de</strong>lin 1997<br />
23<br />
Parathyroid Carcinoma<br />
Parathyroid Carcinoma<br />
Adjuvant therapies<br />
OUR EXPERIENCE (23 cases)<br />
Chemotherapy:<br />
Adriamicina x 3 sessions in 1 patient<br />
Normalization of of calcemia for 3 3 months<br />
Radiotherapy:<br />
External-beam radiotherapy in 1<br />
patient: 50 Gy in 25 sessions<br />
Local recurrence after 5 months<br />
24<br />
OUTCOME<br />
Local recurrence after surgery 30-60%<br />
No<strong>de</strong> metastases 10-30%<br />
Distant metastases 10-20%<br />
Recurrent hyperparathyroidism<br />
Five-years survival rates: 30-70%<br />
Wang 1985 - Fujimoto 1990 - Obara 1993 Hundahl 1999 - Shane 2001<br />
25<br />
131
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