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Full text PDF (3.9MB) - Jurnalul de Chirurgie

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Articole Multimedia <strong>Jurnalul</strong> <strong>de</strong> <strong>Chirurgie</strong>, Iaşi, 2008, Vol. 4, Nr. 2 [ISSN 1584 – 9341]<br />

Parathyroid Carcinoma<br />

Parathyroid Carcinoma<br />

OUR EXPERIENCE (23 cases)<br />

Results<br />

OUR EXPERIENCE<br />

Site of metastases<br />

Median disease-free period:<br />

15 months<br />

(range 2-742<br />

months)<br />

3-years survival: 43%<br />

3-years survival: 43%<br />

5-years survival: 24%<br />

15 died<br />

2 lost FU<br />

6 alive (3 with<br />

recurr)<br />

26<br />

20<br />

18<br />

16<br />

14<br />

12<br />

10<br />

8<br />

6<br />

4<br />

2<br />

0<br />

15<br />

Lung<br />

5 4<br />

Bone Neck<br />

2 1<br />

Med. Retr.<br />

Lung<br />

Bone<br />

Neck<br />

Mediastinum<br />

Retroperitoneum<br />

27<br />

Parathyroid Carcinoma<br />

Parathyroid Carcinoma<br />

Results<br />

variable for different<br />

biological behavior of the tumor<br />

Biological<br />

behaviour<br />

of the tumor<br />

Aggressive course<br />

Slow, indolent progression<br />

28<br />

Once a patient shows a recurrence<br />

it is more likely to have others with<br />

a shorter disease-free periods, like a<br />

figure of<br />

“BUNCH RECURRENCES”<br />

Favia, , W J S 1998<br />

29<br />

Parathyroid Carcinoma<br />

RECURRENCES and REOPERATIONS<br />

Parathyroid Carcinoma<br />

RECURRENCES<br />

OUR EXPERIENCE<br />

n. patients n. reoperations<br />

3 1<br />

3 2<br />

4 3 or more<br />

10/23 patients<br />

had one ore more operations for recurrence<br />

REOPERATIONS<br />

30<br />

31<br />

132

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