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Ghiduri practice hematologice - Spitalul Clinic Municipal de Urgenta ...

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2-cloro<strong>de</strong>oxia<strong>de</strong>nozina<br />

Fludarabina<br />

Vincristina<br />

Vinblastina<br />

Vinorelbina<br />

Bevacizumab<br />

Agenţi orali<br />

Clorambucil<br />

Hidroxiureea<br />

L-fenilalanin mustard<br />

6-tioguanina<br />

Metotrexat<br />

Gefitinib<br />

Erlotinib<br />

Medicamente antiemetice Doza oralã (mg)<br />

Antagonişti serotoninã<br />

(o datã pe zi)<br />

Ondansetron a 16 – 24<br />

Granisetron b 2<br />

Tropisetron c 5<br />

Dolasetron d 100<br />

Palonosetron 0,25 mg i.v. (nu existã formulã oralã disponibilã)<br />

Antagonişti dopaminã<br />

(3 – 4 ori pe zi)<br />

Metoclopramid 20 – 30<br />

Proclorperazin 10 – 20<br />

Domperidon e 20<br />

Metopimazin f 15 – 30<br />

Corticosteroizi<br />

(o datã pe zi)<br />

Dexametazona g 20<br />

Prednisolon 100 – 150<br />

Metilprednisolon h 100<br />

Antagonişti neurochinine 125 mg în ziua 1, urmat <strong>de</strong> 80 mg în zilele<br />

(aprepitant – o datã pe zi) i 2 şi 3 dupã chimioterapie<br />

Altele<br />

(1 – 4 ori pe zi)<br />

Lorazepam 1 – 2<br />

a doza i.v.<strong>de</strong> ondansetron este <strong>de</strong> 8 mg<br />

b doza i.v.<strong>de</strong> granisetron este <strong>de</strong> 1 mg<br />

50

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