Das trockene Auge: Ein Update über Epidemiologie, Diagnose

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und sichere, pharmakologisch basierte Therapie der Keratokonjunktivitis sicca. Fazit für die Praxis Für die Therapie des trockenen Auges werden die Tränensubstitution und die Verbesserung der Tränenfilmqualität sowie der Effizienz der Tränennutzung weiterhin eine wichtige Rolle spielen. Es haben sich jedoch gerade in den letzten Jahren durch eine sehr zeit- und kostenintensive Grundlagenforschung die Kenntnisse der Physiologie und Pathophysiologie der Augenoberfläche und des Tränenfilms exponentiell vermehrt. Nur auf der Basis solcher Erkenntnisse können Konzepte wachsen und schließlich zu nutzbarem Wissen werden. Die Zeit der „ersten Ernte“ scheint jetzt in greifbare Nähe gerückt zu sein. Gelingt es nun, innerhalb weniger Jahre, in neue Dimensionen der Therapie des trockenen Auges vorzustoßen, die in den letzten 20 Jahren kaum erreichbar schienen? Weltweit warten über 100 Millionen betroffene Menschen auf eine Antwort. Korrespondierender Autor Dr. F. 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Adv Exp Med Biol 506:1251–1257 Fachnachricht Moderne Glaukompräparate werden günstiger Die am 1. Januar 2004 in Kraft getretene Reform des Gesundheitssystems macht moderne Glaukommedikamente billiger Glaukom-Patienten sind lebenslang auf ihre Augentropfen angewiesen, wenn sie die Krankheit unter Kontrolle halten wollen. Das Spektrum der Glaukommedikamente reicht von Miotika und Betablockern, die schon seit vielen Jahrzehnten in Gebrauch sind, bis zu den modernsten Prostaglandin-Analoga, wie z. B. dem Wirkstoff Latanoprost. Wegen ihres niedrigeren Preises werden die alten Glaukompräparate in Deutschland aber immer noch relativ häufig verschrieben. Die neue Arzneimittelpreisverordnung könnte hier zu einer Veränderung der Verschreibungspraxis beitragen. Gemäß der neuen Regelung werden die alten Glaukompräparate nämlich verteuert, die innovativen hingegen vergleichsweise erheblich günstiger. Den Augenärzten bietet sich also die Gelegenheit, bei ihren Glaukompatienten zukünftig vermehrt die modernen Wirkstoffe einzusetzen, ohne dabei ihr Budget zu sehr zu strapazieren. Die Zuzahlung des Patienten in der Apotheke ist im Übrigen ähnlich hoch, egal ob er ein altes, weniger wirksames Präparat mit vielen möglichen Nebenwirkungen erhält oder ein modernes, hoch wirksames und besser verträgliches Glaukom-Medikament. Quelle: Deutsches Grünes Kreuz e. V.
Seite 1 und 2: Ophthalmologe 2004 · 101:10-18 DOI
Seite 3 und 4: Zusammenfassung · Abstract Ophthal
Seite 5 und 6: 14 Tabelle 1 Tabelle 2 | Der Ophtha
Seite 7: 16 Cyclosporin A Lokal applizierbar

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