Antibiotic prophylaxis in surgery. (SIGN Guideline No 104)
Antibiotic prophylaxis in surgery. (SIGN Guideline No 104)
Antibiotic prophylaxis in surgery. (SIGN Guideline No 104)
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<strong>Antibiotic</strong> prophylAxis <strong>in</strong> <strong>surgery</strong><br />
14<br />
5.2 recommenDeD <strong>in</strong>DicAtions for surgicAl <strong>Antibiotic</strong> prophylAxis to preVent ssi<br />
Operation Recommendation Odds Ratio NNT Outcome Evidence level<br />
heAD AnD necK<br />
<strong>in</strong>tracranial<br />
craniotomy A <strong>Antibiotic</strong> <strong>prophylaxis</strong> is recommended 0.24 17 Wound <strong>in</strong>fection 1 ++59<br />
+60, 61 1<br />
Wound and shunt<br />
<strong>in</strong>fection<br />
16<br />
16<br />
0.48<br />
0.52<br />
A <strong>Antibiotic</strong> <strong>prophylaxis</strong> is recommended<br />
cerebrosp<strong>in</strong>al fluid (CSF)<br />
shunt<br />
sp<strong>in</strong>al <strong>surgery</strong> A <strong>Antibiotic</strong> <strong>prophylaxis</strong> is recommended 0.36 28 Wound <strong>in</strong>fection 1 ++62<br />
ophthalmic<br />
cataract <strong>surgery</strong> A <strong>Antibiotic</strong> <strong>prophylaxis</strong> is highly recommended 0.36 451 Endophthalmitis 1 ++63<br />
1 +63<br />
Effectiveness is <strong>in</strong>ferred from evidence<br />
about cataract <strong>surgery</strong><br />
glaucoma or corneal grafts b <strong>Antibiotic</strong> <strong>prophylaxis</strong> is recommended<br />
lacrimal <strong>surgery</strong> c <strong>Antibiotic</strong> <strong>prophylaxis</strong> is recommended 0.03 9 Wound <strong>in</strong>fection 2 +64<br />
+65, 66<br />
penetrat<strong>in</strong>g eye <strong>in</strong>jury b <strong>Antibiotic</strong> <strong>prophylaxis</strong> is recommended 0.20 18 Endophthalmitis 1<br />
facial<br />
1 ++,<br />
1 +67-69<br />
A <strong>Antibiotic</strong> <strong>prophylaxis</strong> is recommended 0.26 5 Wound <strong>in</strong>fection<br />
open reduction and <strong>in</strong>ternal<br />
fixation of compound<br />
mandibular fractures<br />
1 ++69<br />
The duration of prophylactic antibiotics should<br />
not be more than 24 hours<br />
A<br />
1 ++70<br />
There was no direct comparison of<br />
prophylactic antibiotic with no antibiotic<br />
b <strong>Antibiotic</strong> <strong>prophylaxis</strong> is recommended<br />
<strong>in</strong>traoral bone graft<strong>in</strong>g<br />
procedures
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