Antibiotic prophylaxis in surgery. (SIGN Guideline No 104)
Antibiotic prophylaxis in surgery. (SIGN Guideline No 104)
Antibiotic prophylaxis in surgery. (SIGN Guideline No 104)
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Operation Recommendation Odds Ratio NNT Outcome Evidence level<br />
heAD AnD necK<br />
facial<br />
A <strong>Antibiotic</strong> <strong>prophylaxis</strong> is recommended 0.21 4 Wound <strong>in</strong>fection 1 +71-74<br />
+71, 73 1<br />
The duration of prophylactic antibiotics should not be<br />
more than 24 hours<br />
A<br />
orthognathic <strong>surgery</strong><br />
1 +71-74<br />
Broad spectrum antibiotics appropriate to oral flora<br />
should be given<br />
b<br />
facial <strong>surgery</strong> (clean) ; <strong>Antibiotic</strong> <strong>prophylaxis</strong> is not recommended<br />
4 75<br />
Effectiveness is <strong>in</strong>ferred from evidence<br />
about other procedures <strong>in</strong>volv<strong>in</strong>g <strong>in</strong>sertion<br />
of prosthetic devices<br />
; <strong>Antibiotic</strong> <strong>prophylaxis</strong> should be considered<br />
facial plastic <strong>surgery</strong><br />
(with implant)<br />
5 <strong>in</strong>DicAtions for surgicAl <strong>Antibiotic</strong> prophylAxis<br />
ear, nose and throat - benign<br />
1 ++76<br />
There was no subgroup of analysis of clean<br />
and clean-contam<strong>in</strong>ated <strong>surgery</strong><br />
A <strong>Antibiotic</strong> <strong>prophylaxis</strong> is not recommended<br />
ear <strong>surgery</strong><br />
(clean/clean-contam<strong>in</strong>ated)<br />
A <strong>Antibiotic</strong> <strong>prophylaxis</strong> is not recommended 1 +77<br />
rout<strong>in</strong>e nose, s<strong>in</strong>us and<br />
endoscopic s<strong>in</strong>us <strong>surgery</strong><br />
1 ++78<br />
The duration of prophylactic antibiotics should not be<br />
more than 24 hours<br />
A<br />
complex septorh<strong>in</strong>oplasty<br />
(<strong>in</strong>clud<strong>in</strong>g grafts)<br />
<strong>No</strong> studies were identified show<strong>in</strong>g<br />
evidence of effectiveness of <strong>prophylaxis</strong><br />
tonsillectomy ; <strong>Antibiotic</strong> <strong>prophylaxis</strong> is not recommended<br />
Adenoidectomy (by curettage) A <strong>Antibiotic</strong> <strong>prophylaxis</strong> is not recommended 1 +79<br />
15
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