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Antibiotic prophylaxis in surgery. (SIGN Guideline No 104)

Antibiotic prophylaxis in surgery. (SIGN Guideline No 104)

Antibiotic prophylaxis in surgery. (SIGN Guideline No 104)

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Operation Recommendation Odds Ratio NNT Outcome Evidence level<br />

AbDomen<br />

gynaecological<br />

D <strong>Antibiotic</strong> <strong>prophylaxis</strong> should be considered 4 120<br />

manual removal of the<br />

placenta<br />

4 120<br />

<strong>Antibiotic</strong> <strong>prophylaxis</strong> is recommended for patients with<br />

proven chlamydia or gonorrhoea <strong>in</strong>fection<br />

D<br />

++ 121 1<br />

upper genital tract<br />

<strong>in</strong>fection<br />

<strong>in</strong>duced abortion A <strong>Antibiotic</strong> <strong>prophylaxis</strong> is highly recommended 0.58 25<br />

A <strong>Antibiotic</strong> <strong>prophylaxis</strong> is not recommended 1 ++122<br />

evacuation of <strong>in</strong>complete<br />

miscarriage<br />

5 <strong>in</strong>DicAtions for surgicAl <strong>Antibiotic</strong> prophylAxis<br />

A <strong>Antibiotic</strong> <strong>prophylaxis</strong> is not recommended 1 ++123<br />

<strong>in</strong>trauter<strong>in</strong>e contraceptive<br />

device (IUCD) <strong>in</strong>sertion<br />

urogenital<br />

+124, 125<br />

transrectal prostate biopsy A <strong>Antibiotic</strong> <strong>prophylaxis</strong> is recommended 0.76 27 Bacteriuria I<br />

1 ++126<br />

ur<strong>in</strong>ary tract<br />

<strong>in</strong>fection<br />

shock wave lithotripsy A <strong>Antibiotic</strong> <strong>prophylaxis</strong> is recommended 0.45 28<br />

0.24 4 urosepsis 1 +127<br />

<strong>Antibiotic</strong> <strong>prophylaxis</strong> is recommended for patients with<br />

stone ≥ 20 mm or with pelvicalyceal dilation<br />

b<br />

percutaneous<br />

nephrolithotomy<br />

1 +127<br />

oral qu<strong>in</strong>olone for one week preoperatively is<br />

recommended<br />

b<br />

1 + ,2 +128,129<br />

Bacteriuria<br />

Post-operative<br />

fever<br />

10<br />

-15<br />

0.13<br />

2.75<br />

b <strong>Antibiotic</strong> <strong>prophylaxis</strong> is recommended<br />

endoscopic ureteric stone<br />

fragmentation/removal<br />

1 ++130<br />

Bacteriuria<br />

Infective<br />

complications<br />

A <strong>Antibiotic</strong> <strong>prophylaxis</strong> is highly recommended 0.35 8<br />

transurethral resection of the<br />

prostate<br />

21

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