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Download PDF - The Pancreapedia

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enclosed in the lymphoreticular tissue of the<br />

spleen and seemed to have reached the organ by<br />

extending through the hilus along the splenic<br />

vessels. In two cases, islets and ductular cells,<br />

and in one case islet cells but not acini, appeared<br />

within the accessory spleen (Fig. 31). <strong>The</strong> intrasplenic<br />

islet was surrounded by a wall of round<br />

cells, possibly as a reflection of immunological<br />

reaction to the foreign tissue. Three of these<br />

hamsters had received carcinogen treatment and<br />

it is not clear whether the carcinogen stimulated<br />

the entrapped embryonic remnant of pancreatic<br />

tissue within the spleen or if the aberrant spleen<br />

was formed around pre existing normal pancreatic<br />

tissue.<br />

4d. Comparative Anatomic-Histological<br />

Pancreatic Data<br />

Generally, the Syrian golden hamster pancreas,<br />

compared to that of man, has the following special<br />

features:<br />

1. A remarkable shape with one head, three<br />

bodies and three tails;<br />

26<br />

2. A specific topography of the gastric lobe,<br />

which lies in an ante-peritoneal position;<br />

3. <strong>The</strong> relationship of the pancreas to the spleen;<br />

unlike in humans, the pancreas tail does not<br />

anchor in the hilus of the spleen;<br />

4. <strong>The</strong> presence of omental fat connecting the<br />

tail of the gastric and splenic lobes;<br />

5. <strong>The</strong> anastomosing artery in the omental fat<br />

connecting the left and right gastroepiploic<br />

arteries;<br />

6. <strong>The</strong> right gastric and the right gastroepiploic<br />

arteries derive from a common artery arising<br />

from the celiac stem;<br />

7. <strong>The</strong> presence of the common duct formed by<br />

the pancreatic and common bile duct;<br />

8. <strong>The</strong> absence of a sphincter on the terminal<br />

(duodenal) end of the common duct;<br />

9. <strong>The</strong> absence of intramural glands around the<br />

pancreatic ducts; and<br />

10. An even distribution of islets throughout the<br />

pancreas.

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