Sedimentation, electrophoresis

Advantages of the analytical ultracentrifugation
No standards are required
AUC is sensitive, precise, accurate and robust (yes – all at a time!)
No interactions with a stationary phase or matrix
Wide range of molar masses can be investigated in the same
experiment – works well for peptides to viruses.
No protein modifications required
No change in mobile phase – your protein is examined in exactly the
same solvent in which you want to study it
Theory of sedimentation is well understood