Gram-negative facultative anaerobic rods

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The consequences of recurrent enteric infections in childhood • Growth retardation due to malabsorption (average: 8.2 cm until 7 years of age; later the child can catch up some growth retardation if infections seize) • An intellectual retardation of about 10 IQ points (The brain and synapses develop primarily during the first two years of life) • A weakened immune system („Fitness cost” associated with a predisposition to infections) • Infection with particular pathogens <strong>negative</strong>ly impact development even without enteric symptoms (enteroaggregative E. coli, cryptosporidium)
Genetic susceptibility to infection by enteropathogenic bacteria • Salmonella: some IL, HLA, IFNGR genes, TNFA • Helicobacter pylori: some IL genes, IFNGR1, TNFA • Vibrio cholerae O1: blood group 0 • Clostridium difficile: IL-8 • Enteroaggregative E. coli: IL-8
Page 1 and 2: The normal gastrointestinal flora G
Page 3 and 4: The normal human gastrointestinal f
Page 5 and 6: Ingestion of lactobacillus strain r
Page 7 and 8: Enterobacteriaceae: most important
Page 9 and 10: Klebsiella pneumoniae Klebsiella ox
Page 11 and 12: Eosin-methylene blue agar Selective
Page 13 and 14: SSI Bi VA Klebsiella DC EM Br
Page 15 and 16: Klebsiella growing on blood agar pl
Page 17 and 18: Serratia marcescens growing on bloo
Page 19 and 20: Uropathogenic E. coli • Causes 90
Page 21 and 22: Enterobacteriaceae: Antibiotic resi
Page 23 and 24: β-lactamase enzymes The most impor
Page 25: Conditions promoting the developmen
Page 29 and 30: Enteropathogenic (dyspepsia) E. col
Page 31 and 32: Enteroinvasive E. coli (EIEC) • S
Page 33 and 34: Enteroaggregative E. coli (EAEC)
Page 35 and 36: Vibrionaceae family • Most import
Page 37 and 38: Vibrio cholerae • Natural habitat
Page 39 and 40: Cholera (2) • Diagnosis: isolatio
Page 42 and 43: Other vibrios • Halophile vibrios
Page 44 and 45: Campylobacter - Gram stain
Page 46 and 47: Recorded cases of campylobacterosis
Page 48 and 49: Helicobacter pylori • About 50% o
Page 50 and 51: Therapy: Helicobacter pylori - ceph
Page 52 and 53: Helicobacter pylori: pathogenicity
Page 54: Thank you for your attention

Gram-negative facultative anaerobic rods

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