Gram-negative facultative anaerobic rods

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Enterotoxin producing E. coli (ETEC) • The causative agent of „travellers’ diarrhea” prevalent in developing countries • symptoms: serious „watery diarrhea”; affecting the small intestine • Pathogenicity factors: usually located on plasmids • Serotypes: diverse • Identification: demonstration of pathogenicity genes with PCR → underdiagnosed - adhesion factors (colonization factors) – usually on fimbriae; types sepcific for particular animal species exist - toxins: LT (heat labile), ST (heat stable) • Therapy: antibiotics, fluid replacement
Enteroinvasive E. coli (EIEC) • Symptoms are same as those of shigellosis (bloody diarrhea - dysentery) • EIEC strains carry the same virulence plasmid and virulence genes as shigellae • EIEC strains are often lactose <strong>negative</strong> and nonmotile • EIEC O antigens are also related to those of shigellas • Transmission: food, contact (not as efficient as with shigellas) • Most common serogroup: O124
Page 1 and 2: The normal gastrointestinal flora G
Page 3 and 4: The normal human gastrointestinal f
Page 5 and 6: Ingestion of lactobacillus strain r
Page 7 and 8: Enterobacteriaceae: most important
Page 9 and 10: Klebsiella pneumoniae Klebsiella ox
Page 11 and 12: Eosin-methylene blue agar Selective
Page 13 and 14: SSI Bi VA Klebsiella DC EM Br
Page 15 and 16: Klebsiella growing on blood agar pl
Page 17 and 18: Serratia marcescens growing on bloo
Page 19 and 20: Uropathogenic E. coli • Causes 90
Page 21 and 22: Enterobacteriaceae: Antibiotic resi
Page 23 and 24: β-lactamase enzymes The most impor
Page 25 and 26: Conditions promoting the developmen
Page 27 and 28: Genetic susceptibility to infection
Page 29: Enteropathogenic (dyspepsia) E. col
Page 33 and 34: Enteroaggregative E. coli (EAEC)
Page 35 and 36: Vibrionaceae family • Most import
Page 37 and 38: Vibrio cholerae • Natural habitat
Page 39 and 40: Cholera (2) • Diagnosis: isolatio
Page 42 and 43: Other vibrios • Halophile vibrios
Page 44 and 45: Campylobacter - Gram stain
Page 46 and 47: Recorded cases of campylobacterosis
Page 48 and 49: Helicobacter pylori • About 50% o
Page 50 and 51: Therapy: Helicobacter pylori - ceph
Page 52 and 53: Helicobacter pylori: pathogenicity
Page 54: Thank you for your attention

Gram-negative facultative anaerobic rods

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